Protein Alignment Ptx1 and pax3a

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_571352.1
• Gene: pax3a / 30532
• ZFINID: ZDB-GENE-980526-52
• Length: 509
• Species: Danio rerio
• Alignment Length: 359
• Identity: 110/359 - (30%)
• Similarity: 151/359 - (42%)
• Gaps: 76/359 - (21%)

  Fly   205 NNFQTSSTSSISNRSRDRKDGN------------RSVNETTIKTENI------SSSGHDEPMTTS 251
            ||  ..|.||||...|.:..||            |.:.|...:.::.      ..|.|.:..:..
Zfish   146 NN--VPSVSSISRMLRCKFGGNGDEDEDDDEVEKREIEENERRAKHSIDGILGDRSSHSDEGSDV 208

  Fly   252 GEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRR 316
            ..||....|.| |||.||.||::||:|||..|.|..|||:.||||:|....||||||:|||.|||
Zfish   209 DSEPGLPLKRK-QRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRR 272

  Fly   317 AKWRKR----ERNAMNAAVAAADFKSGFGTQFM---QPF--ADDSLYSSYPYNNWTKVPSPLGTK 372
            |:|||:    :..|.|..:     ..||....|   ||:  ||    |.||.::.::|.....|.
Zfish   273 ARWRKQAGANQLMAFNHLI-----PGGFPPSAMSSLQPYQLAD----SPYPPSSISQVSEQPSTV 328

  Fly   373 PFPWPVNP-------LGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPG---SMGSSLSNTSN 427
            ..|.|:.|       ||| ..|....:|..|.::|..|.:...:.....||   .:..|:||...
Zfish   329 HRPQPLPPTSVHQSGLGS-GPGAQEGSSAYCLSSGRHGFSGYSDGYVAAPGHANPVNPSISNGLP 392

  Fly   428 VGAVGAPCPYTTPANPYM------YRSAAEPCMSSSMSSSI-ATLRLKAKQHASAGFGSPYSAPS 485
            ...:|...|...|..|..      .....||  |:.|.:|. ::.||:|..      |.|.....
Zfish   393 SQVMGLLNPGAVPHQPQSDFALSPLTGGLEP--STGMPASCHSSQRLEALP------GLPSMPAL 449

  Fly   486 PVSRS------NSAGLS-----ACQYTGVGVTDV 508
            |.|:|      :|.|.|     :.||:..|.:.|
Zfish   450 PSSQSYCPSSYSSPGYSVDHVASYQYSQYGQSKV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	35/55 (64%)
pax3a	NP_571352.1	PAX	34..159	CDD:128645	7/14 (50%)
		Homeodomain	221..277	CDD:459649	35/55 (64%)
		Pax7	350..394	CDD:403540	9/43 (21%)