Protein Alignment Ptx1 and otx2b

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_571326.1
• Gene: otx2b / 30501
• ZFINID: ZDB-GENE-980526-406
• Length: 289
• Species: Danio rerio
• Alignment Length: 277
• Identity: 87/277 - (31%)
• Similarity: 119/277 - (42%)
• Gaps: 68/277 - (24%)

  Fly   248 MTTSGEE--------PKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLT 304
            :||||.:        |...:|   |||:||.||..||..||..|::.||||:..|||:|:..||.
Zfish    17 LTTSGMDLLHPSVGYPATPRK---QRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLP 78

  Fly   305 EARVRVWFKNRRAKWRKRERNAMN-------------AAVAAADFKSGFGTQFMQPFADDSLYSS 356
            |:||:|||||||||.|::::...|             :....|..:||...||..|.:     :|
Zfish    79 ESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKSSPAREASSESGASGQFTPPSS-----TS 138

  Fly   357 YPYNNWTKVP----SPLGTKPFPWPVNPLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGS 417
            .|..:.|..|    ||....|...|::...|.:     |.|.....|.|||.:         .|.
Zfish   139 VPAISTTTAPVSIWSPASISPLSDPLSTSSSCM-----QRSYPMTYTQASGYS---------QGY 189

  Fly   418 MGSSLSNTSNVGAVGAPC-PYTTPANPYMYRSAAEPCMS-SSMSSSIATLRLKAKQHASAGFGSP 480
            .||    ||..|  |..| .|.||    |:.....|..: |.|||:..|..|..         ||
Zfish   190 AGS----TSYFG--GMDCGSYLTP----MHHQLTGPGSTLSPMSSNAVTSHLNQ---------SP 235

  Fly   481 YSAPSPVSRSNSAGLSA 497
            .|.|:....::..|.::
Zfish   236 ASLPTQGYGASGLGFNS 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	33/55 (60%)
otx2b	NP_571326.1	Homeodomain	39..94	CDD:459649	33/54 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..142		10/53 (19%)
		TF_Otx	153..234	CDD:427350	30/113 (27%)