Protein Alignment Ptx1 and Pax2

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: XP_006231505.2
• Gene: Pax2 / 293992
• RGDID: 1305568
• Length: 432
• Species: Rattus norvegicus
• Alignment Length: 388
• Identity: 75/388 - (19%)
• Similarity: 112/388 - (28%)
• Gaps: 153/388 - (39%)

  Fly   128 PAISSLMPI--SSLSHLHHSAGQDLVGGYSQHPHHTVVPPHTPKHEPLEKLRIWAETGDFRDSHS 190
            |::||:..|  :.:....|.. .|..|.....|.||:||                         |
  Rat   130 PSVSSINRIIRTKVQQPFHPT-PDGAGTGVTAPGHTIVP-------------------------S 168

  Fly   191 SMTAVANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNETTIKTE--NISSSGHDEPMTT--- 250
            :.:...:|..:..:.::..:....|. ||...|   |...|..:.|:  :|...|....:.|
  Rat   169 TASPPVSSASNDPVGSYSINGILGIP-RSNGEK---RKREEVEVYTDPAHIRGGGGLHLVWTLRD 229

  Fly   251 --SGEEPKNDKK----NKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVR 309
              .|..|..|.:    :.|:..:...||.|||:.|:..|.|..|||:
  Rat   230 VSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDV------------------ 276

  Fly   310 VWFKNRRAKWRKRERNAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPF 374
              |:                  |:...||..|.::..|.....|         .:|.|.|...
  Rat   277 --FQ------------------ASEHIKSEQGNEYSLPALTPGL---------DEVKSSLSAS-- 310

  Fly   375 PWPVNP-LGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPCPYT 438
               .|| |||.|:|                       ....|...|..:::|            |
  Rat   311 ---TNPELGSNVSG-----------------------TQTYPVVTGRDMAST------------T 337

  Fly   439 TPANPYMYRSAAEPCMSSSMSSSIATLRLKAKQHASAGFGSPYSAPSPVSRSNSAGLSACQYT 501
            .|..|        |.:..:...|..|..|......|...|:|||.|              |||
  Rat   338 LPGYP--------PHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHP--------------QYT 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	12/55 (22%)
Pax2	XP_006231505.2	PAX	16..140	CDD:128645	4/9 (44%)
		Pax2_C	305..>390	CDD:463563	28/136 (21%)