Protein Alignment Ptx1 and NKX2-8

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 119
• Identity: 38/119 - (31%)
• Similarity: 59/119 - (49%)
• Gaps: 12/119 - (10%)

  Fly   228 SVNETTIKTENISSSGHDEPMTTSGEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMS 292
            |.:|::::|....||........|   |.:|.:.:::|  |..|:..|..|||..|.:.||....
Human    53 SSDESSLETSPPDSSQRPSARPAS---PGSDAEKRKKR--RVLFSKAQTLELERRFRQQRYLSAP 112

  Fly   293 TREEIAMWTNLTEARVRVWFKNRRAKWRKRERNAMNAA-----VAAADFKSGFG 341
            .||::|....||..:|::||:|.|.| .||.| |..||     .|:|:..:..|
Human   113 EREQLASLLRLTPTQVKIWFQNHRYK-LKRAR-APGAAESPDLAASAELHAAPG 164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	21/55 (38%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		8/36 (22%)
		Homeodomain	85..141	CDD:459649	21/58 (36%)