Protein Alignment Ptx1 and Otx1

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_037241.2
• Gene: Otx1 / 25646
• RGDID: 3237
• Length: 355
• Species: Rattus norvegicus
• Alignment Length: 387
• Identity: 99/387 - (25%)
• Similarity: 140/387 - (36%)
• Gaps: 114/387 - (29%)

  Fly   262 KRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNA 326
            ::|||:||.||..||..||..|::.||||:..|||:|:..||.|:||:|||||||||.|:::
  Rat    36 RKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQ--- 97

  Fly   327 MNAAVAAADFKSGFGT----------------------QFMQPFADDSLYSSYPYNNWTKVPSPL 369
                      :||.||                      ||..|....|..||...::.:
  Rat    98 ----------QSGNGTKSRPVKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSAS------ 146

  Fly   370 GTKPFPWPVNPLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGS--SLSNTSNVGAVG 432
                    .||..:..||           .|.:.||.:.:.::....|:.|  |:|..|...:|.
  Rat   147 --------ANPAAAAAAG-----------LGGNPVAAASSLSTPTASSIWSPASISPGSAPASVS 192

  Fly   433 APCPYTTPANPYMYRSAAEPCMSSSMSSSIATLRLKAKQHASAG--FGSPYSAPSPVSRSNSAGL 495
            .|.|...|:|        ..||..|:::..||...........|  :|..|.||   |.|...|:
  Rat   193 VPEPLGAPSN--------ASCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPAP---SSSYFGGV 246

  Fly   496 SACQYTGVGVTDVVXENALGALLNQHQHHLQHFSGGSVGGSGVPNGMQQHSGNMLHHSNLGLDHS 560
            ....|                |...|.||..|...        |......:|:..||.:.   |.
  Rat   247 DCSSY----------------LAPMHSHHHPHQLS--------PMAPSSMAGHHHHHPHA---HH 284

  Fly   561 DLGLVGGGPSNHQDEGNHSLEGSN------------KSPMEAPLANSSNNNNNDNDDEDVID 610
            .|....|...:|....:|...|.:            |.|..|..:::...|.|..|..|..|
  Rat   285 PLSQSSGHHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPAAAAASSAWKLNFNSPDCLDYKD 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	33/55 (60%)
Otx1	NP_037241.2	Homeodomain	39..95	CDD:459649	33/55 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	92..144		12/64 (19%)
		TF_Otx	178..274	CDD:427350	29/130 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..306		12/59 (20%)