Protein Alignment Ptx1 and Shox2

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_037160.2
• Gene: Shox2 / 25546
• RGDID: 3674
• Length: 331
• Species: Rattus norvegicus
• Alignment Length: 501
• Identity: 120/501 - (23%)
• Similarity: 155/501 - (30%)
• Gaps: 248/501 - (49%)

  Fly     2 DRSS-AVGGCGGGGGLGVGVVTSSATALGPGGLTNGGGGVVSGALNGLEAMSAESTGLCLQDLVS 65
            |||| ||...|||||.|.|         |.||   ||||
  Rat    49 DRSSPAVRAAGGGGGAGGG---------GGGG---GGGG-------------------------- 75

  Fly    66 AGTANGAGSAGSAESATTTSTALSSGSTGSSTVNGGGSSTSGTEHLHSHHSLHDSSSSVSISPAI 130
             |.|.|.|:.|.|                     |||.|
  Rat    76 -GGAGGGGAGGGA---------------------GGGRS-------------------------- 92

  Fly   131 SSLMPISSLSHLHHSAGQDLVGGYSQHPHHTVVPPHTPKHEPLEKLRIWAETGDFRDSHSSMTAV 195
                                                     |:.:|.:.|
  Rat    93 -----------------------------------------PVRELDMGA--------------- 101

  Fly   196 ANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSGEEPKNDKK 260
                                  ..|.|:.|:..:.|       :|....|......|.|.:...|
  Rat   102 ----------------------AERSREPGSPRLTE-------VSPELKDRKEDAKGMEDEGQTK 137

  Fly   261 NKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERN 325
            .| |||.||:||.:||.|||..|....|||...|||::....|:||||:|||:|||||.||:| |
  Rat   138 IK-QRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQE-N 200

  Fly   326 AMNAAV---AAADFKS-------GFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPFPWPVNP 380
            .::..|   ||:.|::       ..|...| ||..||..:..|.:  .:|.:.|          .
  Rat   201 QLHKGVLIGAASQFEACRVAPYVNVGALRM-PFQQDSHCNVTPLS--FQVQAQL----------Q 252

  Fly   381 LGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPCPYTT-PANPY 444
            |.|.||..||....:                                   :.|..||.. ||.|:
  Rat   253 LDSAVAHAHHHLHPH-----------------------------------LAAHAPYMMFPAPPF 282

  Fly   445 ---------------MYRSAAEPCMSSSMSSSIATLRLKAKQHASA 475
                           ...:||....::|.:||||.||||||:||:|
  Rat   283 GLPLATLAADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAA 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	31/55 (56%)
Shox2	NP_037160.2	Homeodomain	141..197	CDD:459649	31/55 (56%)
		OAR	311..327	CDD:461067	11/15 (73%)