DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptx1 and Drgx

DIOPT Version :9

Sequence 1:	NP_001138130.2	Gene:	Ptx1 / 43664	FlyBaseID:	FBgn0020912	Length:	610	Species:	Drosophila melanogaster
Sequence 2:	NP_665710.2	Gene:	Drgx / 252880	RGDID:	628616	Length:	263	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	86/257 - (33%)
Similarity:	121/257 - (47%)	Gaps:	50/257 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 KRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNA 326
            ::|||.||.||.|||:.||..|::..|||:.||||:||..|||||||:|||:||||||||.||.|
  Rat    31 RKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRKTERGA 95

  Fly   327 MNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPFPWPVNPLGSMVAGNHH- 390
            .:....|           .:|.|:   .:..|..|   :.||           |.|....|...
  Rat    96 SDQEPGA-----------KEPMAE---VTPPPVRN---INSP-----------PPGDQARGKKEA 132

  Fly   391 ---QNSVNCFNTGASGVAVSMNNASMLPGSM------GSSLSNTSNVGAVGAP-CPYTTPANPYM 445
               |.|:. ...|.:|...    .|.|||::      ..:||:.:::  .|.| |....| :|..
  Rat   133 LEAQQSLG-RTVGPAGPFF----PSCLPGTLLNTATYAQALSHVASL--KGGPLCSCCVP-DPMG 189

  Fly   446 YRSAAEPCMSSSMSSSIATLRLKAKQHASAGFGSPYSAPSPVSRSNSAGLSACQYTGVGVTD 507
            ..........|:.::|:|.||:||::|:.|...|....|   |.|:|.|.::.|....|..|
  Rat   190 LSFLPTYGCQSNRTASVAALRMKAREHSEAVLQSANLLP---STSSSPGPASKQVPPEGSQD 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeobox	268..320	CDD:278475	34/51 (67%)
Drgx	NP_665710.2	Homeobox	37..90	CDD:395001	35/52 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	88..135		16/74 (22%)
		OAR	201..218	CDD:397759	7/16 (44%)
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	204..217		6/12 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..263		10/33 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910