Protein Alignment Ptx1 and OTP

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_115485.1
• Gene: OTP / 23440
• HGNCID: 8518
• Length: 325
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 85/297 - (28%)
• Similarity: 133/297 - (44%)
• Gaps: 80/297 - (26%)

  Fly   209 TSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSGEEPKNDKKNKRQRRQRTHFTS 273
            |.::.::|.:..|::.|.:.       ..|.|.:|..:     |::        :|:|.||.||.
Human    69 TPASLAVSAKDPDKQPGPQG-------GPNPSQAGQQQ-----GQQ--------KQKRHRTRFTP 113

  Fly   274 QQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNA------------ 326
            .||.|||.:|::..|||:..|||:|:...|||:||:|||:||||||:||::..
Human   114 AQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPT 178

  Fly   327 ------MNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPFPWPVNPLG--- 382
                  .:||.|||   :..|.......|:|:        .|.....| |....|.| ..||
Human   179 PGLPQFPSAAAAAA---AAMGDSLCSFHANDT--------RWAAAAMP-GVSQLPLP-PALGRQQ 230

  Fly   383 ---------SMVAGNHHQNSVNCFNT--GASGVAVSMN-NASMLPGSMGSSLSNTSNVGAVGAPC 435
                     |:.|| ...||:...|:  |::|..:..: .....||.:.:||...|||.  |:|.
Human   231 AMAQSLSQCSLAAG-PPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVS--GSPQ 292

  Fly   436 PYTTPANPYMYRSAAEPCMSSSMSSSIATLRLKAKQH 472
            ..::|.:..::|           .:|||:||.||.:|
Human   293 LCSSPDSSDVWR-----------GTSIASLRRKALEH 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	32/55 (58%)
OTP	NP_115485.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..112		12/62 (19%)
		Homeodomain	106..156	CDD:459649	27/49 (55%)
		OAR	303..320	CDD:461067	9/27 (33%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	306..319		8/13 (62%)