Protein Alignment Ptx1 and Prrx1

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_035257.1
• Gene: Prrx1 / 18933
• MGIID: 97712
• Length: 245
• Species: Mus musculus
• Alignment Length: 291
• Identity: 89/291 - (30%)
• Similarity: 127/291 - (43%)
• Gaps: 80/291 - (27%)

  Fly   194 AVANSLDST-HLNNFQTSSTSSISNRSRDRKDG-------NRSVNE---TTIKTENISSSGHDEP 247
            |:...|||. :|:..|.....|:|:.....:.|       :.||.|   :.:::..: :||.|.|
Mouse    14 ALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADESVGEAGRSLLESPGL-TSGSDTP 77

  Fly   248 MTTSGEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWF 312
            ...:.:....:||.::|||.||.|.|.|||.||..|.|..|||...||::|...|||||||:|||
Mouse    78 QQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWF 142

  Fly   313 KNRRAKWRKRERNAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPFPWP 377
            :|||||:|:.|| ||.|...|                  ||..||. .:.|.|..|:..:|.|.|
Mouse   143 QNRRAKFRRNER-AMLANKNA------------------SLLKSYS-GDVTAVEQPIVPRPAPRP 187

  Fly   378 VNPLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPCPYTTPAN 442
            .:.|                                   |.|:: |..|.:....|.|...:||
Mouse   188 TDYL-----------------------------------SWGTA-SPYSAMATYSATCANNSPA- 215

  Fly   443 PYMYRSAAEPCMSSSMSSSIATLRLKAKQHA 473
                       ...:|::|||.||||||:::
Mouse   216 -----------QGINMANSIANLRLKAKEYS 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	34/55 (62%)
Prrx1	NP_035257.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24		4/9 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..103		15/49 (31%)
		Homeodomain	99..151	CDD:459649	31/51 (61%)
		OAR	219..235	CDD:461067	10/15 (67%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	222..235		9/12 (75%)