Protein Alignment Ptx1 and Hoxd3

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_034598.2
• Gene: Hoxd3 / 15434
• MGIID: 96207
• Length: 433
• Species: Mus musculus
• Alignment Length: 553
• Identity: 114/553 - (20%)
• Similarity: 176/553 - (31%)
• Gaps: 225/553 - (40%)

  Fly    74 SAGSAESATTTSTALSSGS----------TGSSTVNGGGSSTSGTEHLHSHHSLHDSSSSVSISP 128
            ||.|.:|:.........|:          ||:|...|||:...|         |:.........|
Mouse    66 SACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGNQPPG---------LNSEQQPPQPPP 121

  Fly   129 AISSLMPISSLSHLHHSAGQDLVGGYSQHPHHTVVPPHTPKHE----PLEKLRIWAETGDFRDSH 189
                                         |....:||.:|.:.    |.:|.:
Mouse   122 -----------------------------PPPPTLPPSSPTNPGSGVPAKKTK------------ 145

  Fly   190 SSMTAVANSLDSTHLNNFQTSSTSSISNR----SRDRKDGNRSVNETTIKTENISSSGHDEPMTT 250
            ..::|              :||:|:||.:    .::.:..::..|......||........|.:
Mouse   146 GGLSA--------------SSSSSTISKQIFPWMKESRQNSKQKNSCATSGENCEDKSPPGPAS- 195

  Fly   251 SGEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNR 315
                          :|.||.:||.||.|||..|..|||.....|.|:|...||||.::::||:||
Mouse   196 --------------KRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNR 246

  Fly   316 RAKWRKRERNAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPFPWPVNP 380
            |.|::|.::                        |...|:            ||.|..|...|  |
Mouse   247 RMKYKKDQK------------------------AKGILH------------SPAGQSPERSP--P 273

  Fly   381 LGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPCPYTTPA---- 441
            ||                 ||:|..........:||.            |..||.|   ||
Mouse   274 LG-----------------GAAGHVAYSGQLPPVPGL------------AYDAPSP---PAFAKS 306

  Fly   442 NPYMYRSAAEPCMSSSMSSSIATLRLKAKQHASAGFGSPYSAPSPVSRSNSAGLSACQYTGVGVT 506
            .|.||..||   .::.:||.:...:         .:.:|...|.|:: ||..|.::....|..|
Mouse   307 QPNMYGLAA---YTAPLSSCLPQQK---------RYPAPEFEPHPMA-SNGGGFASANLQGSPV- 357

  Fly   507 DVVXENALGALLNQHQHHLQHFSGGSVGGSGVP-NGMQQHSGNMLHHSNLGLDHSDLGLVGGGPS 570
                                 :.||:...|..| :|...:.|::.|.|:..:|:|....:   |.
Mouse   358 ---------------------YVGGNFVDSMAPTSGPVFNLGHLSHPSSASVDYSCAAQI---PG 398

  Fly   571 NHQD------------EGNHSLEGSNKSPMEAP 591
            ||..            ..:||.:|  :.| |||
Mouse   399 NHHHGPCDPHPTYTDLSAHHSSQG--RLP-EAP 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	27/55 (49%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..198		30/210 (14%)
		Antp-type hexapeptide	161..166		0/4 (0%)
		Homeodomain	196..252	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..280		11/52 (21%)
		DUF4074	370..431	CDD:463833	16/65 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..433		7/31 (23%)