Protein Alignment Ptx1 and Dmbx1

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: XP_017175446.1
• Gene: Dmbx1 / 140477
• MGIID: 2153518
• Length: 389
• Species: Mus musculus
• Alignment Length: 381
• Identity: 95/381 - (24%)
• Similarity: 149/381 - (39%)
• Gaps: 122/381 - (32%)

  Fly   204 LNNFQTSSTSSIS----------NRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSGEEPKND 258
            :|.:...:.:|:|          .:::...|...||:..|: .|.::.....:.:.    |.:..
Mouse    14 VNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTL-AERLAGCTFQDIIL----EARYG 73

  Fly   259 KKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRE 323
            .::::|||.||.||:|||:.||.||.:..|||:..||.:||.|||.||||:|||||||||:||::
Mouse    74 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQ 138

  Fly   324 RNAMNAAV---AAADFKSGFGTQFMQPFADDSLYSSYP--------------------------- 358
            |:.....:   ..|:...|.| :...|.:|..|.:..|
Mouse   139 RSLQKEQLQKQKEAEGSHGEG-KVEAPASDTQLETEQPPGLPSGDPPAELQLSLSEQSASESAPE 202

  Fly   359 -------------------YNNWTKVP-----SPLGTKPFP---WPVNPLGSMVAGNH------- 389
                               ..:.:|||     ||....|..   .|..|.|.::..:|
Mouse   203 DQLDREEDSRAEEPKAEKSPGSESKVPGCKRGSPKADSPGSLAITPAAPGGGLLGPSHSYSSSPL 267

  Fly   390 -----------HQNSVN------CFNTG--------ASGVAVSMNNASMLPGS--------MGSS 421
                       |..:.|      .|..|        |:..||.....:|.|.|        ...|
Mouse   268 SLFRLQEQFRQHMAATNNLMHYSSFEVGGPAPAAAAAAAAAVPYLGVNMAPLSSLHCQSYYQSLS 332

  Fly   422 LSNTSNVGAVGAPCPYTTPANPYMYRSAAEPCMS--SSMSSSIATLRLKAKQHASA 475
            .:..::.|..|:|   ..||.|    :...|..:  :|.::||..|||:|||||::
Mouse   333 AAAAAHQGVWGSP---LLPAPP----TGLAPASAALNSKTTSIENLRLRAKQHAAS 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	36/55 (65%)
Dmbx1	XP_017175446.1	Homeodomain	80..136	CDD:459649	36/55 (65%)