Protein Alignment Ptx1 and Cdx4

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_031700.1
• Gene: Cdx4 / 12592
• MGIID: 88362
• Length: 282
• Species: Mus musculus
• Alignment Length: 237
• Identity: 57/237 - (24%)
• Similarity: 100/237 - (42%)
• Gaps: 46/237 - (19%)

  Fly   101 GGSSTSGTEHLHSHHSLHDSSSSVSISPAISSLMPISSLSHLHHSAGQDLVGGYSQHPHHTVVPP 165
            |||||:|                |..|....|.:|.|:.:      ...:...|..:||.:.:.|
Mouse    22 GGSSTAG----------------VGTSGGSGSPLPASNFT------AAPVYPHYVGYPHMSNMDP 64

  Fly   166 HTPKHEPLEKLRIWAET-GDFRDSHSSMTAVANSLDSTHLNN-----FQTSSTSSISNRSRDRKD 224
            |.|      .|..|:.. ...|:..|:.....:::.:..:|:     |.:...|::...|.....
Mouse    65 HGP------SLGAWSSPYSPPREDWSTYPGPPSTMGTVPMNDMTSPVFGSPDYSTLGPTSGASNG 123

  Fly   225 GN--RSVNETTIKTENISSSGHDEPMTTSGEEP--------KNDKKNKRQRRQRTHFTSQQLQEL 279
            |:  .:.:|:.:..:: .:||...| :.|...|        :...|.:.:.:.|..:|..|..||
Mouse   124 GSLPDAASESLVSLDS-GTSGATSP-SRSRHSPYAWMRKTVQVTGKTRTKEKYRVVYTDHQRLEL 186

  Fly   280 EHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRK 321
            |..|..|||..:..:.|:|:...|:|.:|::||:|||||.||
Mouse   187 EKEFHCNRYITIRRKSELAVNLGLSERQVKIWFQNRRAKERK 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	22/55 (40%)
Cdx4	NP_031700.1	Caudal_act	13..168	CDD:461413	32/175 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	13..36		8/29 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	98..156		11/59 (19%)
		Homeodomain	173..228	CDD:459649	22/54 (41%)