Protein Alignment Ptx1 and Alx4

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_031468.1
• Gene: Alx4 / 11695
• MGIID: 108359
• Length: 399
• Species: Mus musculus
• Alignment Length: 509
• Identity: 132/509 - (25%)
• Similarity: 192/509 - (37%)
• Gaps: 182/509 - (35%)

  Fly     4 SSAVGGCGGGGGLGVGVVTSSATALGPGGLTNGGGGVVSGALNGLEAMSAESTGLCLQDLVSAGT 68
            ||...|..||...|...:::.|...|.|                 :|.|....|...|||
Mouse    31 SSPFRGFPGGDKFGTTFLSAGAKGQGFG-----------------DAKSRARYGAGQQDL----- 73

  Fly    69 ANGAGSAGSAESATTTSTALSSGSTGSSTVNGGGSSTSGTEHLHSHHSLHDSSSSVSISPAISSL 133
                  |...||        |||:.|                  |.:.......:....||
Mouse    74 ------AAPLES--------SSGARG------------------SFNKFQPQPPTPQPPPA---- 102

  Fly   134 MPISSLSHLHHSAG------------QDLVGGYS---QHPHHTV-----VPPHTPKHEPLEKLRI 178
             |.:..:||:...|            |:..||::   |.|.:..     .|...|..||:
Mouse   103 -PPAPPAHLYLQRGACKTPPDGSLKLQEGSGGHNAALQVPCYAKESNLGEPELPPDSEPV----- 161

  Fly   179 WAETGDFRDSHSSMTAVANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNETTIK-TENISSS 242
                               .:|:::|                       ||.||..| .::.:|:
Mouse   162 -------------------GMDNSYL-----------------------SVKETGAKGPQDRASA 184

  Fly   243 GHDEPMTTSGEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEAR 307
            ....|:..:..|....||    ||.||.|||.||:|||..|.:..|||:..||::||.|:|||||
Mouse   185 EIPSPLEKTDSESNKGKK----RRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEAR 245

  Fly   308 VRVWFKNRRAKWRKRERNAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKV--PSPLG 370
            |:|||:|||||||||||......|     ::.|.|.:..|....:       .|:.::  ||.:|
Mouse   246 VQVWFQNRRAKWRKRERFGQMQQV-----RTHFSTAYELPLLTRA-------ENYAQIQNPSWIG 298

  Fly   371 ----TKPFP---WPVNPLGSMVAGNHHQNSVNCFNTGASGVA--VSMNNASMLPGSMGSSLSNT- 425
                ..|.|   .|.:|:.:.::.:.|..     .:|||.|:  :|::.|       ||.:..|
Mouse   299 NNGAASPVPACVVPCDPVPACMSPHAHPP-----GSGASSVSDFLSVSGA-------GSHVGQTH 351

  Fly   426 --SNVGAVGAPCPYTTPANPYM--YRSAAEPCMSSSMSSSIATLRLKAKQHASA 475
              |..||.|        .:|.:  |....||   ...:||||.||:|||:|::|
Mouse   352 MGSLFGAAG--------ISPGLNGYEMNGEP---DRKTSSIAALRMKAKEHSAA 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	36/55 (65%)
Alx4	NP_031468.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..133		18/106 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..206		10/38 (26%)
		Homeodomain	203..259	CDD:459649	36/55 (65%)
		OAR	375..393	CDD:461067	10/17 (59%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	379..392		9/12 (75%)