Protein Alignment Ptx1 and Vsx1

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_473409.1
• Gene: Vsx1 / 114889
• MGIID: 1890816
• Length: 363
• Species: Mus musculus
• Alignment Length: 245
• Identity: 72/245 - (29%)
• Similarity: 106/245 - (43%)
• Gaps: 72/245 - (29%)

  Fly   235 KTENISSSGHDEPMTTSGEEPKNDKK------NKRQRRQRTHFTSQQLQELEHTFSRNRYPDMST 293
            ::|::|:|..|.|     .|.|||.|      .:::||.||.||:.||:|||..|....|||:..
Mouse   141 RSESVSTSDGDSP-----SEEKNDPKMSLILGKRKKRRHRTVFTAHQLEELEKAFGEAHYPDVYA 200

  Fly   294 REEIAMWTNLTEARVRVWFKNRRAKWRKRERNAMNAAVAA----------------------ADF 336
            ||.:|..|.|.|.|::|||:||||||||||:....::|.|                      ||.
Mouse   201 REMLAAKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLNSADS 265

  Fly   337 KSGF-----------GTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPFPWP----VNPLGSMVA 386
            ..|.           .|...:|.::|.|...:.:::..|..:.....|...|    .||
Mouse   266 LQGSCAPWLLGMHKKSTGMRKPESEDKLAGLWEFDHLKKGANKDEDGPERGPDETTQNP------ 324

  Fly   387 GNHHQNSVNCFNTGASGVAVSMNNAS------MLPGSMGSSLSNTSNVGA 430
                :||:       ..||:.::::|      |.||| .:.|.....|||
Mouse   325 ----ENSL-------EDVAIDLSSSSRQETKKMPPGS-STQLPQPPQVGA 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	31/55 (56%)
Vsx1	NP_473409.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		Octapeptide motif	31..38
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..66
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	122..166		10/29 (34%)
		Nuclear localization signal. /evidence=ECO:0000255	168..173		0/4 (0%)
		Homeodomain	172..228	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..363		18/81 (22%)