Protein Alignment Ptx1 and Pax3

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_446162.1
• Gene: Pax3 / 114502
• RGDID: 620431
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 336
• Identity: 105/336 - (31%)
• Similarity: 136/336 - (40%)
• Gaps: 64/336 - (19%)

  Fly   211 STSSISN--RSR-----------DRKDGNRSVNETTIKTENISSSGHDEPMTTSG----EEPKND 258
            |.||||.  ||:           :||:...|..:.....:.|.|.....|.:..|    .||...
  Rat   150 SVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLP 214

  Fly   259 KKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKR- 322
            .|.| |||.||.||::||:|||..|.|..|||:.||||:|....||||||:|||.||||:|||:
  Rat   215 LKRK-QRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA 278

  Fly   323 ---ERNAMNAAVAAADFKSGFGTQFMQ--PFADDSLYSSYPYNNWTKVPSPLGTKPFPWPVNPL- 381
               :..|.|..:     ..||....|.  |....|..|..|.:....|..|..|...|.|:.|.
  Rat   279 GANQLMAFNHLI-----PGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPST 338

  Fly   382 --GSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGS---------MGSSLSN-----TSNVGA 430
              .|.:..|...:|..|..:...|  .|....|.:|.|         :|:.||.     .:|.|.
  Rat   339 VHQSTIPSNADSSSAYCLPSTRHG--FSSYTDSFVPPSGPSNPMNPAIGNGLSPQVMGLLTNHGG 401

  Fly   431 VGAPCPYTTPANPYM---YRSAAEPCMSSSMSSSIATLRLK-AKQHASAGFGSPYSAPSPVSRSN 491
            |    |: .|...|.   .....||..:.|.|.|   .||: .|...|.....||..|:    .:
  Rat   402 V----PH-QPQTDYALSPLTGGLEPTTTVSASCS---QRLEHMKNVDSLPTSQPYCPPT----YS 454

  Fly   492 SAGLSACQYTG 502
            :.|.|....||
  Rat   455 TTGYSMDPVTG 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	35/55 (64%)
Pax3	NP_446162.1	PAX	34..159	CDD:128645	5/8 (63%)
		Homeodomain	220..276	CDD:459649	35/55 (64%)
		Pax7	347..391	CDD:403540	11/45 (24%)