Protein Alignment Ptx1 and uncx

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001305673.1
• Gene: uncx / 100492016
• XenbaseID: XB-GENE-920201
• Length: 483
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 111/523 - (21%)
• Similarity: 169/523 - (32%)
• Gaps: 219/523 - (41%)

  Fly   133 LMPISSLSHLHHSAGQDLVG--GYSQHPHHTVVPPHTPKHEPLEKLRIWAETGDFRDSH---SSM 192
            :|....|.|.|...|..:.|  |:          |:...|..:.:|.          ||   |:.
 Frog     1 MMDSRILEHPHAQFGGSMSGMVGF----------PYPLGHHHVYELA----------SHQLQSAA 45

  Fly   193 TAVANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSGE-EPK 256
            .||..|:|.. ||.   |.|:|:             :|.|.:.......:|..:....|.. :|.
 Frog    46 AAVPFSIDGL-LNG---SCTASV-------------INPTPLLPSGCGLNGDSQQYKLSDSIDPD 93

  Fly   257 NDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRK 321
            .:....::||.||:||..||:|||..|:.:.|||:..||.:|:..:|.|:||:|||:||||||||
 Frog    94 KESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRK 158

  Fly   322 RE------------------------------------------------RNA---------MNA 329
            :|                                                ||.         |:.
 Frog   159 KENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKQEKKMLRNQNRLQHSPGDMSL 223

  Fly   330 AVAAADFKSGF------------------------------GTQFMQ------------------ 346
            ...::|..||.                              |..|.|
 Frog   224 HTPSSDSDSGLSQNLDSSSLESSHPDMGQSRSQTQASCDQTGQAFFQSQRNTGQRDRVSDKESPV 288

  Fly   347 ---------------------PFADDSLYSSYPYNNWTKVPSPLGTKP---------FPWPV-NP 380
                                 ||:.:||.|..|....|.:..|..|.|         ..:|: .|
 Frog   289 EANHNSGLCPNGRGAAFQKLNPFSVESLLSDSPPKRKTGIEFPGLTNPRTLIGKGHFLLYPITQP 353

  Fly   381 LGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPG-SMGSSLSNTSNVGAVGAPCPYTTP---A 441
            ||.:|                ...::..|:|..||. .:..||.|:::    |.|...|:|   .
 Frog   354 LGFIV----------------PQASIKSNSAQELPSPGIKDSLHNSNS----GQPSLNTSPNSAQ 398

  Fly   442 NPYMYRSAAEPCMSSSMSSSIATLRLKAKQH----ASAG------FGSPYSAP-SPVSRSNSAGL 495
            |.|..:..     :|:.|:::...:.:...|    :|:|      ..|.||.| ||.|..:....
 Frog   399 NLYPNKHT-----NSTQSTTLTVCKTENGDHHGATSSSGDTGTEQLDSTYSEPKSPKSLKSDRET 458

  Fly   496 SAC 498
            ..|
 Frog   459 PEC 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	31/55 (56%)
uncx	NP_001305673.1	homeobox domain	101..160		33/58 (57%)
		Homeodomain	102..158	CDD:459649	31/55 (56%)