Protein Alignment Ptx1 and shox2

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001093694.1
• Gene: shox2 / 100101703
• XenbaseID: XB-GENE-480993
• Length: 311
• Species: Xenopus tropicalis
• Alignment Length: 277
• Identity: 91/277 - (32%)
• Similarity: 126/277 - (45%)
• Gaps: 62/277 - (22%)

  Fly   225 GNRS-VNETTIKTENISSSGHDEPMTTSGE--EPKNDKKNK----------RQRRQRTHFTSQQL 276
            |.|| |.|..:..|.|..||..:....|.|  |.|.:.|.:          :|||.||:||.:||
 Frog    68 GARSPVLELDLSVERIRESGSPKLTEVSPEIKERKEELKQQALEEEGQTKIKQRRSRTNFTLEQL 132

  Fly   277 QELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNAMNAAVAAADFKSGFG 341
            .|||..|....|||...|||::....|:||||:|||:|||||.||:| |.::..|..     |.|
 Frog   133 NELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQE-NQLHKGVLI-----GAG 191

  Fly   342 TQF----MQPFAD-DSLYSSYPYNNWTKVPSPLGTKPFPWPVN---PLGSMVAGNHHQNSVNCFN 398
            :||    :.|:.: .:|...:..::...|||      ..:.|.   .|.|.||..||.     .:
 Frog   192 SQFEACRVAPYVNVGALRMPFQQDSHCNVPS------LSFQVQAQLQLDSAVAHAHHH-----LH 245

  Fly   399 TGASGVAVSMNNASMLPG-----SMGSSLSNTSNVGAVGAPCPYTTPANPYMYRSAAEPCMSSSM 458
            ...:..|..|    |.|.     .:.:..:.|:...:|.|               ||....:||.
 Frog   246 PHLTAHAPYM----MFPAPPFGLPLATLAAETATAASVVA---------------AAAAAKTSSK 291

  Fly   459 SSSIATLRLKAKQHASA 475
            :||||.||||||:||:|
 Frog   292 NSSIADLRLKAKKHAAA 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	31/55 (56%)
shox2	NP_001093694.1	Homeodomain	121..177	CDD:459649	31/55 (56%)
		OAR	292..307	CDD:461067	11/14 (79%)