Protein Alignment Cyp4c3 and ERG5

DIOPT Version :10

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 525
• Identity: 114/525 - (21%)
• Similarity: 199/525 - (37%)
• Gaps: 119/525 - (22%)

  Fly    89 KLWGTRIGINRVWQGTAPRV---------LLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLL 144
            |::.|.|.|..||...|.::         ..|.| .:.|.|.|            |.|...|
Yeast    47 KIFATLICILLVWDQVAYQIKKGSIAGPKFKFWP-IIGPFLES------------LDPKFEE--- 95

  Fly   145 TSTDRKWHSRRKILTPAFH-FKILDDFIDVFNE--QSAVLARKLAVEVGSEAF------------ 194
              ...||.|........|| |.::....|:..:  ||:...:...|:|..:..
Yeast    96 --YKAKWASGPLSCVSIFHKFVVIASTRDLARKILQSSKFVKPCVVDVAVKILRPCNWVFLDGKA 158

  Fly   195 ---------NLFPYVTLC----TLDIVCETAMGRRIYAQSNSESEYVKAVY-----------GIG 235
                     .||....|.    :|:.:.:..|.:  :.:.:.|:.|...|:           .:.
Yeast   159 HTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDK--FVRLSKENNYEPQVFFHEMREILCALSLN 221

  Fly   236 S-----IVQSRQAKIWLQSDFIFSLTAEYKLHQ-----SYINTLHGFSNMVIRERKAELAILQEN 290
            |     |.:.:..||   :|..:.:||..:|..     .|..|.:|       ::.|::|:
Yeast   222 SFCGNYITEDQVRKI---ADDYYLVTAALELVNFPIIIPYTKTWYG-------KKTADMAM---- 272

  Fly   291 NNNNNNNAPDAYDDV---GKKKRL--AFLDLLIDASKEG--------TVLSNEDIREEVDTFMFE 342
             ....|.|..|.|.:   ||...:  |:..|:.||....        ...:|::|.|.|.||:|.
Yeast   273 -KIFENCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREFTNKEISEAVFTFLFA 336

  Fly   343 GHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFP 407
            ..|.:|:...|...::...|:...::.||..::..:|..|...:..:..|:|....||::||..|
Yeast   337 SQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRP 401

  Fly   408 SVPMMARMVGEDVNIG-GKIVPAGTQAIIMTY-ALHRNPRVFPKPEQFNPDNFLPENCAGRHPFA 470
            .|.|:..:|.::..:. ....|.|...|...| ||| :|.|:..|::|.|:.::..:.|......
Yeast   402 PVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALH-DPEVYENPDEFIPERWVEGSKASEAKKN 465

  Fly   471 YIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELI-----LRPKDGLRVK 530
            ::.|..||..|:||.:.::    ..:.:|.|:.: ..|....:|.|.|.|     :.|||.|.:.
Yeast   466 WLVFGCGPHVCLGQTYVMI----TFAALLGKFAL-YTDFHHTVTPLSEKIKVFATIFPKDDLLLT 525

  Fly   531 ITPRD 535
            ...||
Yeast   526 FKKRD 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	109/510 (21%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	93/441 (21%)