DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP704B1

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_177109.3	Gene:	CYP704B1 / 843283	AraportID:	AT1G69500	Length:	524	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	145/544 - (26%)
Similarity:	237/544 - (43%)	Gaps:	83/544 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 IFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVIGMQKLWGTRIGINRVWQG 103
            |||..:.:|..         .||...|.:|.|||...:.|.:.:.::  :.|:.:|..:  |...
plant    15 IFLHRWGQRNK---------SGPKTWPLVGAAIEQLTNFDRMHDWLV--EYLYNSRTVV--VPMP 66

  Fly   104 TAPRVLLFEPETVEPILNSQKFVN--KSHDY-DYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFK 165
            ......:.:|..||.:|.: .|.|  |...| .|:...||:|:..|....|..:||..:..|..|
plant    67 FTTYTYIADPINVEYVLKT-NFSNYPKGETYHSYMEVLLGDGIFNSDGELWRKQRKTASFEFASK 130

  Fly   166 ILDDFID-VFNEQSAVLARKLA-VEVGSEAFNLFPYVTLCTLDIVCETAMGRRI--YAQSNSESE 226
            .|.||.. ||.|.|..|...|: .....:..::...:...|||.:|:...|..|  .|....|:.
plant   131 NLRDFSTVVFKEYSLKLFTILSQASFKEQQVDMQELLMRMTLDSICKVGFGVEIGTLAPELPENH 195

  Fly   227 YVKAVYGIGSIVQSRQA-KIWLQSDFIFSLTAEYKLHQSYINTLHGFSNMVIRERKAEL--AILQ 288
            :.||......||..|.. .:|....|: ::.:|..|.:| |..::.|:..|||.|||||  |.:.
plant   196 FAKAFDTANIIVTLRFIDPLWKMKKFL-NIGSEALLGKS-IKVVNDFTYSVIRRRKAELLEAQIS 258

  Fly   289 ENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDA-SKEGTVLSNEDIREEVDTFMFEGHDTTSAAIS 352
            ..|||||||....:|.:.:     |:::..|. |||    :.:.:|:.|..|:..|.|||:..::
plant   259 PTNNNNNNNNKVKHDILSR-----FIEISDDPDSKE----TEKSLRDIVLNFVIAGRDTTATTLT 314

  Fly   353 WTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMD-------------------------M 392
            |.::::..:....|::..||..:..:..|...|..:..|                         :
plant   315 WAIYMIMMNENVAEKLYSELQELEKESAEATNTSLHQYDTEDFNSFNEKVTEFAGLLNYDSLGKL 379

  Fly   393 RYLECCIKDSLRLFPSVPMMARMVGEDVNI-GGKIVPAGTQAIIMTYALHR-------NPRVFPK 449
            .||...|.::|||:|:||...:.|.||..: .|..|.||.....:.|::.|       :..:| |
plant   380 HYLHAVITETLRLYPAVPQDPKGVLEDDMLPNGTKVKAGGMVTYVPYSMGRMEYNWGSDAALF-K 443

  Fly   450 PEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVD----RR 510
            ||::..|... :|.:   ||.:..|.||||.|:|:..|.|:.|..::.:.|.||...|.    :.
plant   444 PERWLKDGVF-QNAS---PFKFTAFQAGPRICLGKDSAYLQMKMAMAILCRFYKFHLVPNHPVKY 504

  Fly   511 EDLTLLGELILRPKDGLRVKITPR 534
            ..:|     ||....||:|.::.|
plant   505 RMMT-----ILSMAHGLKVTVSRR 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	140/519 (27%)
CYP704B1	NP_177109.3	PLN03195	1..524	CDD:215627	145/544 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920