DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP735A2

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_176882.1	Gene:	CYP735A2 / 843031	AraportID:	AT1G67110	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	554	Identity:	147/554 - (26%)
Similarity:	247/554 - (44%)	Gaps:	101/554 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VFLLGSILIFLVVYNK------RRSRLVKYIEK--IPGPAAMPFLGNAIEM-------------N 74
            |.::...||..|:|:.      ...|:.|::|:  |.||......||.|::             :
plant    10 VLVIVMTLILRVLYDSICCYFLTPRRIKKFMERQGITGPKPRLLTGNIIDISKMLSHSASNDCSS 74

  Fly    75 VDHD---ELFNRVIGMQKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFV-NKSHDYDYL 135
            :.|:   .|....:...|.:|.|.   .:|.||.||:.|.|.|.::.:|.....| .||
plant    75 IHHNIVPRLLPHYVSWSKQYGKRF---IMWNGTEPRLCLTETEMIKELLTKHNPVTGKS------ 130

  Fly   136 HPWL---------GEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGS 191
              ||         |.|||.:....||.:|.:..|||....|..:.....|.:.::|.:|..|||.
plant   131 --WLQQQGTKGFIGRGLLMANGEAWHHQRHMAAPAFTRDRLKGYAKHMVECTKMMAERLRKEVGE 193

  Fly   192 EAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLT 256
            |. .:...:...|.||:..|..|        |..:..|.::.:.:::|              .|.
plant   194 EV-EIGEEMRRLTADIISRTEFG--------SSCDKGKELFSLLTVLQ--------------RLC 235

  Fly   257 AEYKLHQSYINT--LHGFSNMVIRERKAE-----LAILQENNNNNNNNAPDAYDDVGKKKRLAFL 314
            |:...|..:..:  |....|..|:..|.|     :.|:....::.......:|.|
plant   236 AQATRHLCFPGSRFLPSKYNREIKSLKTEVERLLMEIIDSRKDSVEIGRSSSYGD---------- 290

  Fly   315 DLL------IDASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELD 373
            |||      :|::|..  |:.:.|.:|..||.|.||:|||..::|||.||..:|.:|:.|.:|:.
plant   291 DLLGLLLNQMDSNKNN--LNVQMIMDECKTFFFTGHETTSLLLTWTLMLLAHNPTWQDNVRDEVR 353

  Fly   374 SIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTY 438
            .:.|.| ..| :::.|..:..|...|.:||||:|...::.||..||:.:|..|:|.|....|...
plant   354 QVCGQD-GVP-SVEQLSSLTSLNKVINESLRLYPPATLLPRMAFEDIKLGDLIIPKGLSIWIPVL 416

  Fly   439 ALHRNPRVFPK-PEQFNPDNFLPENCA-GRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRK 501
            |:|.:..::.: ..:|||:.|...:.| .||   ::||:|||||||||.||::|.|.:::.::.|
plant   417 AIHHSNELWGEDANEFNPERFTTRSFASSRH---FMPFAAGPRNCIGQTFAMMEAKIILAMLVSK 478

  Fly   502 YKIEAVDRREDLTLLGELILRPKDGLRVKITPRD 535
            :.. |:........:..|.::||.|:::.:.|.|
plant   479 FSF-AISENYRHAPIVVLTIKPKYGVQLVLKPLD 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	136/512 (27%)
CYP735A2	NP_176882.1	PLN02290	2..511	CDD:215164	146/552 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960