DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4c3 and CYP86A4

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_171666.1	Gene:	CYP86A4 / 839347	AraportID:	AT1G01600	Length:	554	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	133/548 - (24%)
Similarity:	227/548 - (41%)	Gaps:	86/548 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVI-GMQKLWGT--- 93
            ||.:|:....::.||.||.:|      ||...|.||:...:....|.:...:. .::...||
plant     8 LLVAIVTGYWLWFKRISRWLK------GPRVWPLLGSLPGLIEQRDRMHEWITENLRACGGTYQT 66

  Fly    94 ---RIGINRVWQGTAPRVLLFEPETVEPILNSQKFVN--KSHDY-DYLHPWLGEGLLTSTDRKWH 152
               .:......||..  .:..:|:.:|.:|.: :|.|  |...: ...|..||:|:..|....|.
plant    67 CIFAVPFLAKKQGLV--TVTCDPKNLEHMLKT-RFDNYPKGPTWQSVFHDLLGQGIFNSDGDTWL 128

  Fly   153 SRRKILTPAFHFKILDDFIDVFNEQS------AVLARKLAVEVGSEAFNLFPYVTLCTLDIVCET 211
            .:||.....|..:.|...:..:..:.      .:||   ..:..:|..:|...:...|.|.:|..
plant   129 FQRKTAALEFTTRTLRQAMGRWVNRGIKLRFCPILA---TAQDNAEPVDLQDLILRLTFDNICGL 190

  Fly   212 AMGR--RIYAQSNSESEYVKAVYGIGSIVQSR--------QAKIWLQSDFIFSLTAEYKLHQSYI 266
            |.|:  |..|....|:.:..|..........|        :.|.||      .|..|..|.:| :
plant   191 AFGKDTRTCAPGLPENGFASAFDRATEASLQRFIIPKFMWKLKKWL------GLGLEVSLSRS-L 248

  Fly   267 NTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGTVLSNED 331
            ..:..:...||..||.||...||:..:..::  |.......||..::.|         |.|.:..
plant   249 GEIDEYLAAVINTRKQELMSQQESGTHQRHD--DLLSRFMMKKTESYSD---------TFLQHVA 302

  Fly   332 IREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIF----GDD-----KETPATMK 387
            :     .|:..|.||:|.|:||..:|:..||..::::|.|:.|:.    |.|     .|.|....
plant   303 L-----NFILAGRDTSSVALSWFFWLITMHPTVEDKIVREICSVLIETRGTDDVASWTEEPLGFD 362

  Fly   388 NLMDMRYLECCIKDSLRLFPSVPMMARMV-GEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKP- 450
            .:..:.||:..|.::|||:||||..::.| .:||...|..||||:......||..|....:.:.
plant   363 EIDRLVYLKAAISETLRLYPSVPEDSKHVENDDVLPDGTFVPAGSSVTYSIYAAGRMKSTWGEDC 427

  Fly   451 EQFNPDNFLPE---NCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKI-----EAV 507
            .:|||:.::..   .......:.::.|:||||.|:|:..|.|:.|.:.:.||.::::     ..|
plant   428 LEFNPERWISPIDGKFINHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVVPGHKV 492

  Fly   508 DRREDLTLLGELILRPKDGLRVKITPRD 535
            :::..|||.      .|:||.|.:..||
plant   493 EQKMSLTLF------MKNGLLVNLYKRD 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	123/516 (24%)
CYP86A4	NP_171666.1	PLN03195	5..513	CDD:215627	131/545 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920