DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4c3 and CYP714A2

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_197872.1	Gene:	CYP714A2 / 832559	AraportID:	AT5G24900	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	590	Identity:	131/590 - (22%)
Similarity:	250/590 - (42%)	Gaps:	137/590 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ESILLSKVGQ----VISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIE 72
            ||:::..|..    ||.|     :|.:|..:....|..:.|.|....::.:.||....|.||..|
plant     2 ESLVVHTVNAIWCIVIVG-----IFSVGYHVYGRAVVEQWRMRRSLKLQGVKGPPPSIFNGNVSE 61

  Fly    73 MN--------------VDHD---ELFNRVIGMQKLWGTRIGINRVW---QGTAPRVLLFEPETVE 117
            |.              :.||   .||......:|.:|      |::   .|....:.:..||.|:
plant    62 MQRIQSEAKHCSGDNIISHDYSSSLFPHFDHWRKQYG------RIYTYSTGLKQHLYINHPEMVK 120

  Fly   118 PI--LNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWHSRRKILTPAF-HFKI-------LDDFID 172
            .:  .|:......:|....|:|.||.|::||....|..:|:|:...| |.||       ::..:.
plant   121 ELSQTNTLNLGRITHITKRLNPILGNGIITSNGPHWAHQRRIIAYEFTHDKIKGMVGLMVESAMP 185

  Fly   173 VFNEQSAVLARKLAVEVGSEAFNLFPYVTLCTLDI------VCETAMGRRIYAQSNSESEYVKAV 231
            :.|:...::.|  ..|:|            |.:.:      |....:.:..:..|.|:.   ||:
plant   186 MLNKWEEMVKR--GGEMG------------CDIRVDEDLKDVSADVIAKACFGSSFSKG---KAI 233

  Fly   232 YGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLHGFSNMVIRERK----------AEL-A 285
            :   |:::          |.:.::|     .:|.:...:||::||...:|          .|| :
plant   234 F---SMIR----------DLLTAIT-----KRSVLFRFNGFTDMVFGSKKHGDVDIDALEMELES 280

  Fly   286 ILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDA---SKEGTVLSNEDIR----EEVDTFMFEG 343
            .:.|..........|.:     ||.|  :.|:::.   |.:|.:......|    :...:..|.|
plant   281 SIWETVKEREIECKDTH-----KKDL--MQLILEGAMRSCDGNLWDKSAYRRFVVDNCKSIYFAG 338

  Fly   344 HDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPS 408
            ||:|:.::||.|.||..:|.:|.::   .|.|....|......:::.:::.:...|::::||:|.
plant   339 HDSTAVSVSWCLMLLALNPSWQVKI---RDEILSSCKNGIPDAESIPNLKTVTMVIQETMRLYPP 400

  Fly   409 VPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVF-PKPEQFNPDNF---LPENCAGRHPF 469
            .|::.|...:|:.:|..:||.|.....:..||||:|.:: |....|.|:.|   :.:.|  ::|.
plant   401 APIVGREASKDIRLGDLVVPKGVCIWTLIPALHRDPEIWGPDANDFKPERFSEGISKAC--KYPQ 463

  Fly   470 AYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTL--------LGELILRPKDG 526
            :||||..|||.|:|:.|.::|.|.::|.::.|:         ..||        ..:|::.|:.|
plant   464 SYIPFGLGPRTCVGKNFGMMEVKVLVSLIVSKF---------SFTLSPTYQHSPSHKLLVEPQHG 519

  Fly   527 LRVKI 531
            :.:::
plant   520 VVIRV 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	120/537 (22%)
CYP714A2	NP_197872.1	p450	37..524	CDD:299894	122/548 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960