DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4c3 and CPD

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_196188.1	Gene:	CPD / 830453	AraportID:	AT5G05690	Length:	472	Species:	Arabidopsis thaliana

Alignment Length:	510	Identity:	110/510 - (21%)
Similarity:	191/510 - (37%)	Gaps:	121/510 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VFLLGSILI-FLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEM----NVDHDELF--NRV---- 84
            :.||.||.. ||::..:.|.|.:..   .||...:|.:|...::    ..::.|.|  .||
plant     7 LLLLSSIAAGFLLLLRRTRYRRMGL---PPGSLGLPLIGETFQLIGAYKTENPEPFIDERVARYG 68

  Fly    85 -IGMQKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFV--NKSHDYDYLHP-----WLGE 141
             :.|..|:|            .|.:...:|||       .:||  |:...::..:|     .||:
plant    69 SVFMTHLFG------------EPTIFSADPET-------NRFVLQNEGKLFECSYPASICNLLGK 114

  Fly   142 GLLTSTDRKWHSRRKILTPAF-HFKILDD--FIDV-----FNEQSAVLARKLAVEVGSEAFNLFP 198
            ..|.......|.|...||.:| :..|:.|  .:|:     ||..| ..:|.|.:|   ||..:
plant   115 HSLLLMKGSLHKRMHSLTMSFANSSIIKDHLMLDIDRLVRFNLDS-WSSRVLLME---EAKKI-- 173

  Fly   199 YVTLCTLDIVCETAMGRRIYAQSNS-ESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLH 262
                 |.::..:..|.......|.| ..||:..:.|..|:...           :||.|.. |..
plant   174 -----TFELTVKQLMSFDPGEWSESLRKEYLLVIEGFFSLPLP-----------LFSTTYR-KAI 221

  Fly   263 QSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGTVL 327
            |:........:.:|::.|:.|                    :.|.:::...|..|: |:.:|  .
plant   222 QARRKVAEALTVVVMKRREEE--------------------EEGAERKKDMLAALL-AADDG--F 263

  Fly   328 SNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSI-----------FGDDKE 381
            |:|:|.:.:...:..|::|||..::..:..|...|....::.||.:.|           :.|.|.
plant   264 SDEEIVDFLVALLVAGYETTSTIMTLAVKFLTETPLALAQLKEEHEKIRAMKSDSYSLEWSDYKS 328

  Fly   382 TPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRV 446
            .|.|          :|.:.::||:...:..:.|....||.|.|..:|.|.:......|:|.:|..
plant   329 MPFT----------QCVVNETLRVANIIGGVFRRAMTDVEIKGYKIPKGWKVFSSFRAVHLDPNH 383

  Fly   447 FPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRK 501
            |.....|||..:...:........:.||..|||.|.|.:.|    :..:|..|.:
plant   384 FKDARTFNPWRWQSNSVTTGPSNVFTPFGGGPRLCPGYELA----RVALSVFLHR 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	102/481 (21%)
CPD	NP_196188.1	p450	1..472	CDD:386267	110/510 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010