DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP81F3

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_568025.1	Gene:	CYP81F3 / 829894	AraportID:	AT4G37400	Length:	501	Species:	Arabidopsis thaliana

Alignment Length:	539	Identity:	120/539 - (22%)
Similarity:	225/539 - (41%)	Gaps:	102/539 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 PITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNR-------VI 85
            |:.:|||...|.|       .|:..::......|.::|.||:...:......||:|       :.
plant     9 PLALFLLAYKLFF-------TSKTKRFNLPPSPPYSLPILGHHNLLKPPVHRLFHRLSKTHGPIF 66

  Fly    86 GMQKLWGTRIGINRVWQGTAPRVLLFEPETV---EPILNSQKFVNKSHDYDYLHPWLGEGLLTST 147
            .:|  :|:|..:.......|.:....:.:.:   .|...:.|:|  :::|..:      |.....
plant    67 SLQ--FGSRRAVVISSSSLATQCFTGQNDIILSNRPCFLTAKYV--AYNYTTV------GTAPYG 121

  Fly   148 DRKWHSRRKILTPAFHFKILD-----DFIDVFNEQSAVLARKLAVEVGSEAFNLFPYVTLCTLDI 207
            |. |.:.|:|.:    .:||.     :|:.:..::...:..:|:.:|..| ..|.|.::..|.:.
plant   122 DH-WRNLRRICS----LEILSSNRLTNFLHIRKDEIHRMLTRLSRDVNKE-IELEPLLSDLTFNN 180

  Fly   208 VCETAMGRRIYA-QSNSESE---YVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINT 268
            :.....|:|.|. :.::|.|   :.|.|..|.....:|....:|....:|..:.|.|: ::....
plant   181 IVRMVTGKRYYGDEVHNEEEANVFKKLVADINDCSGARHPGDYLPFMKMFGGSFEKKV-KALAEA 244

  Fly   269 LHGFSNMVIRERKAELAILQENNNNNNN------NAPDAYDDVGKKKRLAFLDLLIDASKEGTVL 327
            :......::.|.|.:    ::.|...|:      |.|:.|.||..|               |.:|
plant   245 MDEILQRLLEECKRD----KDGNTMVNHLLSLQQNEPEYYTDVTIK---------------GLML 290

  Fly   328 SNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDK--ETPATMKNLM 390
            .          .|..|.||::..:.|.:..|..|||..|:...|:|...|.::  :.|    ::.
plant   291 G----------MMIAGTDTSAVTLEWAMSSLLNHPEALEKAKLEIDEKIGQERLIDEP----DIA 341

  Fly   391 DMRYLECCIKDSLRLFPSVPMMA-RMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFN 454
            ::.||:..:.::.||:|:.|::. |...||:.:||..||.||..::..:|:||:|.::.:||:|.
plant   342 NLPYLQNIVSETFRLYPAAPLLVPRSPTEDIKVGGYDVPRGTMVMVNAWAIHRDPELWNEPEKFK 406

  Fly   455 PDNFLPENCAGRHPFAY--IPFSAGPRNC----IGQKFAILEEKAVISTV-LRKYKIEAVDRRED 512
            |:.|......||....:  :||..|.|:|    :|||...|...::|... .:|...||:|..|
plant   407 PERFNGGEGGGRGEDVHKLMPFGNGRRSCPGAGLGQKIVTLALGSLIQCFDWQKVNGEAIDMTE- 470

  Fly   513 LTLLGELILRPKDGLRVKI 531
                     .|...:|.||
plant   471 ---------TPGMAMRKKI 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	111/506 (22%)
CYP81F3	NP_568025.1	p450	40..482	CDD:299894	111/501 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910