DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4c3 and CYP702A6

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_680696.2	Gene:	CYP702A6 / 827207	AraportID:	AT4G15396	Length:	475	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	102/544 - (18%)
Similarity:	199/544 - (36%)	Gaps:	118/544 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ITVFLLGSILIFLVVYNKRRSRLVKYIEKI-------------PGPAAMPFLGNAIEMNVDHDEL 80
            :.::...::::.|:|        ||....|             ||....|.:|...|....||.:
plant     2 VDLYEFWAVIVSLIV--------VKLCHSIYQWRNPKSNGELPPGSMGYPIIGETFEFMKPHDAI 58

  Fly    81 -----------------FNRVIGMQKLWGTRIGINRVWQGT--APRVLLFEPETVEPILNSQK-F 125
                             ...:.|.:.:..|.||:|.....|  .|.:    |:::..:..:.. |
plant    59 QLPTFVKEKVLRHGPVFRTSLFGGKVIISTDIGLNMEIAKTNHIPGM----PKSLARLFGANNLF 119

  Fly   126 VNK---SHDYDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAV 187
            |||   .|.....:.:||                  :.|...::|.|...:........|||.::
plant   120 VNKDTHKHARSLTNQFLG------------------SQALKLRMLQDIDFLVRTHLKEGARKGSL 166

  Fly   188 EVGSEAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFI 252
            ::......:.       ::.:.:..||       ..|.:..|.:    ::..:...:.|....:.
plant   167 DIKETTSKII-------IECLAKKVMG-------EMEPDAAKEL----TLCWTFFPREWFGFAWN 213

  Fly   253 FSLTAEYKLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLL 317
            ...|..|::               ::.|...:.:|:|.......:..:..|        .|..:.
plant   214 IPGTGVYRM---------------VKARNRMMKVLKETVLKKRASGEELGD--------FFKTIF 255

  Fly   318 IDASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGD---- 378
            .|..:....:|.|...|.:.|.....::||.|.::.|:.|:..||:..:.:..|.:.|..|
plant   256 GDTERGVKTISLESATEYIFTLFLLANETTPAVLAATIKLISDHPKVMQELQREHEGIVRDKIEK 320

  Fly   379 DKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYA-LHR 442
            :::...|.::...|.:.:..|.:|||:..:||.:.|::..:...|...:|||.  |.|.|. :|.
plant   321 NEKADLTWEDYKSMTFTQMVINESLRITSTVPTVLRIIDHEFQFGEYTIPAGW--IFMGYPYVHF 383

  Fly   443 NPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAV 507
            |...:..|..|||..:..::.:......||||.:|.|.|:|.:|..| :.|:....|.:|:   .
plant   384 NAEKYDDPLAFNPWRWKGKDLSAIVSRTYIPFGSGSRLCVGAEFVKL-KMAIFIHHLSRYR---W 444

  Fly   508 DRREDLTLLGELILRPKDGLRVKI 531
            ..:.:.|||...:|....|..|:|
plant   445 SMKTETTLLRRFVLILPRGSDVQI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	96/499 (19%)
CYP702A6	NP_680696.2	p450	9..454	CDD:299894	97/521 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010