DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP702A5

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001078393.1	Gene:	CYP702A5 / 827206	AraportID:	AT4G15393	Length:	467	Species:	Arabidopsis thaliana

Alignment Length:	543	Identity:	108/543 - (19%)
Similarity:	207/543 - (38%)	Gaps:	116/543 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ITVFLLGSILIFLVVYNKRRSRLVKYI----------EKIPGPAAMPFLGNAIEMNVDHDEL--- 80
            :.|:...::::.|:|.     :|..:|          :..||....|.:|...|....||.:
plant     2 VEVYEFWAVIVSLIVV-----KLCHWIYQWKNPKGNGKLPPGSMGYPIIGETFEFMKLHDAIQLP 61

  Fly    81 --------------FNRVIGMQKLWGTRIGINRVWQGT--APRVLLFEPETVEPILNSQK-FVNK 128
                          ...:.|.:.:..|.||:|.....|  .|.:    |:::|.:..:.. ||||
plant    62 TFVKEKLLRHGPVFRTSLFGGKVIISTDIGLNMEIAKTNHIPGM----PKSLERLFGATNLFVNK 122

  Fly   129 ---SHDYDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVG 190
               .|.....:.:||                  :.|...:::.|...:........|||..::|.
plant   123 DTHKHARSLTNQFLG------------------SQALKLRMIQDIDFLARTHMKEGARKGCLDVK 169

  Fly   191 SEAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSL 255
            ..|..:       .::.:.:..||       ..|.|..|.:    ::..:...:.|.:..:.|..
plant   170 ETASKI-------VIECLSKKVMG-------EMEPEAAKEL----TLCWTFFPRDWFRFAWNFPG 216

  Fly   256 TAEYKLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDA 320
            |..|::.::....:......|:::|.:                       |||....|..:..|.
plant   217 TGVYRIVKARNRMMKVIKETVVKKRAS-----------------------GKKLGEFFETIFGDT 258

  Fly   321 SKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGD----DKE 381
              |...:|.|...|.:.|.....::||...::.|:.|:..:|:..:.:..|.:.|..|    |:.
plant   259 --ESVTMSIEIATEYIFTLFVLANETTPGVLAATIKLISDNPKVMQELRREHEGIVQDKIKKDET 321

  Fly   382 TPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYA-LHRNPR 445
            ...|.::...|.:.:..|.:|||:..:||.:.|::..::..|...:|||.  |.|.|. :|.||.
plant   322 ADLTWEDYKSMTFTQMVINESLRITSTVPTVLRIIDHEIQFGDYTIPAGW--IFMGYPYVHFNPE 384

  Fly   446 VFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLR-KYKIEAVDR 509
            .:..|..|||..:..::.:......|:||.:|.|.|:|.:|..|:....|..:.| ::.::|
plant   385 KYDDPLAFNPWRWKGKDLSTIVSKTYLPFGSGTRLCVGAEFVKLQMAIFIHHLFRYRWSMKA--- 446

  Fly   510 REDLTLLGELILRPKDGLRVKIT 532
              :.|||...||....|..|:|:
plant   447 --ETTLLRRFILVLPRGSDVQIS 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	102/500 (20%)
CYP702A5	NP_001078393.1	p450	30..448	CDD:386267	95/489 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010