DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP97B3

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_193247.2	Gene:	CYP97B3 / 827177	AraportID:	AT4G15110	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	501	Identity:	126/501 - (25%)
Similarity:	219/501 - (43%)	Gaps:	96/501 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 GINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHD----YDYLHPWLGEGLLTSTDRKWHSRRK 156
            ||.::..|....|::.:|.....:|....|   |:|    .:.|.|.:|:||:.:....|..||:
plant   112 GIYKLAFGPKAFVVISDPIIARHVLRENAF---SYDKGVLAEILEPIMGKGLIPADLDTWKLRRR 173

  Fly   157 ILTPAFHFKILDDFIDVFNE-------QSAVLARKLAVEVGSEAFNL---FPYVTLCTLDIVCET 211
            .:|||||...|:..:.||::       :|..|.|:.....|.:...|   ..:.:| .|||:
plant   174 AITPAFHKLYLEAMVKVFSDCSEKMILKSEKLIREKETSSGEDTIELDLEAEFSSL-ALDII--- 234

  Fly   212 AMGRRI----YAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFS---------LTAEYKLHQ 263
              |..:    :.....||..:||||  |::.::..     :|.|.|.         :....:..|
plant   235 --GLSVFNYDFGSVTKESPVIKAVY--GTLFEAEH-----RSTFYFPYWNFPPARWIVPRQRKFQ 290

  Fly   264 SYINTLHGFSNMVIRERK-----AELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKE 323
            |.:..::...:.:|:..|     .::..|||.:..|..:|             :.|..|:|  ..
plant   291 SDLKIINDCLDGLIQNAKETRQETDVEKLQERDYTNLKDA-------------SLLRFLVD--MR 340

  Fly   324 GTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKN 388
            |..:.:..:|:::.|.:..||:||:|.::|.:|||..:||...:...|:|::.|   :.|.|.::
plant   341 GVDIDDRQLRDDLMTMLIAGHETTAAVLTWAVFLLSQNPEKIRKAQAEIDAVLG---QGPPTYES 402

  Fly   389 LMDMRYLECCIKDSLRLFPSVPMMARMV--------GEDVNIGGKIVPAGTQAIIMTYALHRNPR 445
            :..:.|:...:.:.|||||..|::.|..        |......|..||.||...|..|.|||:|.
plant   403 MKKLEYIRLIVVEVLRLFPQPPLLIRRTLKPETLPGGHKGEKEGHKVPKGTDIFISVYNLHRSPY 467

  Fly   446 VFPKPEQFNPDNFLP-------ENCAGRHP---------------FAYIPFSAGPRNCIGQKFAI 488
            .:..|..|.|:.||.       |..||..|               ||::||..|||.|||.:||:
plant   468 FWDNPHDFEPERFLRTKESNGIEGWAGFDPSRSPGALYPNEIIADFAFLPFGGGPRKCIGDQFAL 532

  Fly   489 LEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVKITPR 534
            :|....::.:.:|:.:|.....|.:.|:....:..|:|:..|:..|
plant   533 MESTVALAMLFQKFDVELRGTPESVELVSGATIHAKNGMWCKLKRR 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	124/496 (25%)
CYP97B3	NP_193247.2	PLN02738	45..580	CDD:215393	126/501 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920