DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and LUT1

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_190881.2	Gene:	LUT1 / 824479	AraportID:	AT3G53130	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	478	Identity:	113/478 - (23%)
Similarity:	210/478 - (43%)	Gaps:	76/478 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 WGTRIG-INRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWHSR 154
            |....| |.|:..|....|::.:|...:.:|.:.....|....:......|.|...:....|.:|
plant   104 WMNEYGPIYRLAAGPRNFVIVSDPAIAKHVLRNYPKYAKGLVAEVSEFLFGSGFAIAEGPLWTAR 168

  Fly   155 RKILTPAFHFKILDDFID-VFNEQSAVLARKLA--VEVGSEAFNLFPYVTLCTLDIVCETAMGRR 216
            |:.:.|:.|.:.|...:: ||.:.:..|..||.  .|.|| |.|:....:..|||::     |..
plant   169 RRAVVPSLHRRYLSVIVERVFCKCAERLVEKLQPYAEDGS-AVNMEAKFSQMTLDVI-----GLS 227

  Fly   217 IYAQS----NSESEYVKAVYGIGSIVQSRQAKI---WLQSDFIFSLTAEYKLHQSYINTLHGFSN 274
            ::..:    .::|..::|||......:.|...:   |                     .:.....
plant   228 LFNYNFDSLTTDSPVIEAVYTALKEAELRSTDLLPYW---------------------KIDALCK 271

  Fly   275 MVIRERKAELAI----------------LQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKE 323
            :|.|:.|||.|:                :.|......|:  :.|.:......|.||    .||:|
plant   272 IVPRQVKAEKAVTLIRETVEDLIAKCKEIVEREGERIND--EEYVNDADPSILRFL----LASRE 330

  Fly   324 GTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKN 388
              .:|:..:|:::.:.:..||:||.:.::|||:||..:.....:..||:|.:.  :...|| .::
plant   331 --EVSSVQLRDDLLSMLVAGHETTGSVLTWTLYLLSKNSSALRKAQEEVDRVL--EGRNPA-FED 390

  Fly   389 LMDMRYLECCIKDSLRLFPSVPMMARMVG-EDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQ 452
            :.:::|:..||.:|:||:|..|::.|... .|:..|...|..|...:|..|.:||:..|:.|.|:
plant   391 IKELKYITRCINESMRLYPHPPVLIRRAQVPDILPGNYKVNTGQDIMISVYNIHRSSEVWEKAEE 455

  Fly   453 FNPDNFLPENCAGRHP------FAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRRE 511
            |.|:.|   :..|..|      |.:||||.|||.|:|.:||::|....::..|::..:|.|. .:
plant   456 FLPERF---DIDGAIPNETNTDFKFIPFSGGPRKCVGDQFALMEAIVALAVFLQRLNVELVP-DQ 516

  Fly   512 DLTLLGELILRPKDGLRVKITPR 534
            .:::.....:...:||.:|::.|
plant   517 TISMTTGATIHTTNGLYMKVSQR 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	111/473 (23%)
LUT1	NP_190881.2	PLN02936	56..539	CDD:178524	112/476 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920