DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP71A26

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_680106.1	Gene:	CYP71A26 / 823985	AraportID:	AT3G48270	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	120/524 - (22%)
Similarity:	221/524 - (42%)	Gaps:	91/524 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVIGMQKLWGT 93
            |..|||.||:..:.:...|:.:..|....:|.|..:|.:||..::. .|..  ..:..:...:|.
plant     3 IMFFLLCSIIFVVTIIIFRKQKRGKKRNTLPSPPGLPLIGNLHQLG-RHPH--RSLCSLSHRYGP 64

  Fly    94 RIGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHD-------------------YDYLHPWL 139
            .:.::   .|..|.:::...|....:|       |:||                   :|......
plant    65 LMLLH---FGRVPVLVVSSAELARDVL-------KTHDRVFASRPRSKIFEKLLYDKHDVASAPY 119

  Fly   140 GEGLLTSTDRKWHSRRKI-LTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNLFPYVTLC 203
            ||        .|...:.: :...|..|::..|.:|..|:.:::..|:...: |...||...:...
plant   120 GE--------YWRQMKSVCVLHLFSNKMVRSFREVREEEISLMMEKIRKSI-SLPVNLSKILVSL 175

  Fly   204 TLDIVCETAMGRRIYAQSNSESEYVK------AVYGIGSIVQSRQAKIWLQ-SDFIFSLTAEYKL 261
            |.|::|:.|:||: |.......|.::      ..:.:||.|.      ||. .|:|..|..:.
plant   176 TNDVICKVALGRK-YGGETDFKELMERLNKLLGTFSVGSYVP------WLAWIDWIRGLDCQL-- 231

  Fly   262 HQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGTV 326
             :...|.:..|...|::                     |..|  |.:....|:|:|:...::.||
plant   232 -EKTANDVDKFFERVVQ---------------------DHVD--GNRDMTDFVDVLLAIQRDKTV 272

  Fly   327 ---LSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKN 388
               ::...|:..|......|.||:|..:.|.:..|..||:..:|:.||:.:|..|  ::..:.:.
plant   273 GFEINRVSIKAIVMNVFVGGTDTSSTLMEWAMTELLRHPKCLKRLQEEVRTICKD--KSSVSEEE 335

  Fly   389 LMDMRYLECCIKDSLRLFPSVPMMA-RMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVF-PKPE 451
            :.:|.||:..||::|||.|.:|:|. ....:||.:|...:|||||.:|..:|:.|....: |..|
plant   336 IQNMSYLKAVIKEALRLHPPLPLMVPHESTQDVRLGDHHIPAGTQVLINAWAIGREAATWGPDVE 400

  Fly   452 QFNPDNFLPENCAGR-HPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIE-AVDRREDLT 514
            :|.|:..|..:...| ..|..|||.:|.|.|....||::..:.|::.::.::... :|:..||.|
plant   401 EFRPERHLDSSVDYRGQAFELIPFGSGRRICPAISFAVVLNEVVLANLVHRFDWRLSVESTEDQT 465

  Fly   515 LLGE 518
            .:.|
plant   466 EVAE 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	112/494 (23%)
CYP71A26	NP_680106.1	p450	21..481	CDD:299894	114/506 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910