DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP71B35

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_189262.1	Gene:	CYP71B35 / 822235	AraportID:	AT3G26310	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	489	Identity:	111/489 - (22%)
Similarity:	203/489 - (41%)	Gaps:	97/489 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEM-NVDHDELFNRVIGMQKLWGTR 94
            :||   :.|.|.|:|.::.  .|| .:.|.|...|.:||..:: .:.|..|:.    :.|.:|.
plant    10 IFL---VCILLAVFNHKKH--PKY-RQFPCPPGFPIIGNLHQIGELPHQTLWK----LSKKYGP- 63

  Fly    95 IGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHD----------------YDYLHPWLGEGL 143
              :..:..|..|.|::...:|...:|       :.||                |:||     :..
plant    64 --VMHLMLGRVPTVVVSSSDTARQVL-------RVHDLHCCTRPSLSGPRELSYNYL-----DIA 114

  Fly   144 LTSTDRKWHSRRKIL------TPAFHF--KILDD----FIDVFNEQSAVLARKLAVEVGSEAFNL 196
            .:..|..|...||:.      |...|.  .|.|:    .||...|.:   ::|..|.:.::...|
plant   115 FSPYDDYWKEVRKLCVQELFSTKQVHSIQPIKDEEVKKMIDSIAESA---SQKNPVNLNNKCLEL 176

  Fly   197 FPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKL 261
                   |:.:||.||.|........:...:.|.|         |:|...|.|   || .|::..
plant   177 -------TVSVVCRTAFGVSFEGTVLNSDRFNKIV---------REALEMLGS---FS-AADFIP 221

  Fly   262 HQSY-INTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGT 325
            :..: |:.|.|......|.::...|..::..:.:.....:..:|        |:|||:...||..
plant   222 YVGWIIDVLTGLQGRRERSKRDLNAFFEQMFDLHKEGKKEGNED--------FVDLLLRLEKEEA 278

  Fly   326 VLSNEDI-REEVDTFMFE----GHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPAT 385
            ||.|:.: |..:...:.:    |.||::..::|.:..|..:|...::|..|:.:..|:  .:..:
plant   279 VLGNDKLTRNHIKAILLDVLLAGIDTSAITMTWAMTELARNPRVMKKVQSEIRTQMGN--RSMIS 341

  Fly   386 MKNLMDMRYLECCIKDSLRLFPSVP-MMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPK 449
            .:::..:.||:..||::.||.|:.| ::.|....:.:|.|..:|..|:..:..:|:.|:|..:..
plant   342 FEDMDQLEYLKMVIKETWRLHPTTPLLLPREAMSEFDINGYTIPVKTRLHVNVWAIGRDPDTWKD 406

  Fly   450 PEQFNPDNFLPEN--CAGRHPFAYIPFSAGPRNC 481
            ||.|.|:.|:..|  ..|:| |..:||..|.|.|
plant   407 PEVFLPERFMDNNIDAKGQH-FELLPFGGGRRIC 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	103/461 (22%)
CYP71B35	NP_189262.1	p450	7..496	CDD:386267	111/489 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910