DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP71B34

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_189261.1	Gene:	CYP71B34 / 822234	AraportID:	AT3G26300	Length:	500	Species:	Arabidopsis thaliana

Alignment Length:	552	Identity:	127/552 - (23%)
Similarity:	214/552 - (38%)	Gaps:	127/552 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEM-NVDHDELFNRVIGMQKLWGTRIG 96
            |:..|.|.:.|:|.:..|  .|....|.|...|.:||..:: .:.|..|:.    :.|.:|.
plant     9 LIFVICILVAVFNHKNRR--NYQRTPPSPPGCPIIGNLHQLGELPHQSLWK----LSKKYGP--- 64

  Fly    97 INRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHD----------------YDYLHPWLGEGLLT 145
            :..:..|..|.|::...||.:..|       |.||                |:||     :...:
plant    65 VMLLKLGRVPTVIVSSSETAKQAL-------KIHDLHCCSRPGFAGARELSYNYL-----DIAFS 117

  Fly   146 STDRKWHSRRKI-LTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEA-----FNLFPYVTLCT 204
            ..|..|...||: :...|..|.:.....:.:|:    .:||...:...|     .||...:...|
plant   118 PYDDYWKEVRKLAVQELFSSKQVHSIQPIKDEE----VKKLIDSISESAAQKTPINLNKTLLALT 178

  Fly   205 LDIVCETAMGRRIYAQ-SNSE--SEYVK-AVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSY 265
            :.:||.||........ .|||  :..|: |:..:||         :..||||           .|
plant   179 VSVVCRTAFSVNFEGTVLNSERFNNIVREALEMLGS---------FSASDFI-----------PY 223

  Fly   266 INTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYD---DVGKKKRLA----FLDLLIDASKE 323
            :..:...           |..||.....:..:....|:   |:.|:|:..    |:|||:...||
plant   224 VGRIIDL-----------LTGLQGRRERSMRDLDAFYEQMFDLHKQKKEEGSEDFVDLLLRLEKE 277

  Fly   324 GTVLSNEDI-REEVDTFMFE----GHDTTSAAISWTLFLLGCHPEYQERVVEELDS-------IF 376
            ..||.|:.: |..:...:.:    |.||::..::|.:..|..:|...::|..|:.|       |.
plant   278 EAVLGNDKLTRNHIKAILMDVLLAGMDTSAITMTWAMAELAKNPRVMKKVQSEIRSQIKNKERIS 342

  Fly   377 GDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMM-ARMVGEDVNIGGKIVPAGTQAIIMTYAL 440
            .||.:         .:.||:..||::.||.|:.|:: .|....:..|.|..:|..|:..:..:|:
plant   343 FDDTD---------KLEYLKMVIKETWRLHPTTPLLIPREAMSEFEINGYTIPVKTRLHVNVWAI 398

  Fly   441 HRNPRVFPKPEQFNPDNFLPEN--CAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKY- 502
            .|:|..:..||.|.|:.|...|  ..|:| |..:||..|.|.|..........:..::.:|..:
plant   399 GRDPDTWKDPEVFLPERFTDNNIDAKGQH-FELLPFGGGRRMCPAVYMGTTMVEFGLANLLYHFD 462

  Fly   503 -------KIEAVDRRE--DLTL--LGELILRP 523
                   |::.:|..|  .||:  ..||||.|
plant   463 WKLPEGMKVDDIDMEEAPGLTVNKKNELILVP 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	120/526 (23%)
CYP71B34	NP_189261.1	p450	7..498	CDD:299894	127/552 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910