DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP72A13

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_188084.1	Gene:	CYP72A13 / 820694	AraportID:	AT3G14660	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	126/517 - (24%)
Similarity:	232/517 - (44%)	Gaps:	87/517 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 MAESILLSKVGQVISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMN 74
            |.|| .|.:.|...:.|:|    |:|.:.....:..:.||:.:...:.|. |..:|:   .::|.
plant    34 MLES-YLRRQGLAGTPYTP----LVGDLKRNFSMLAEARSKPINLTDDIT-PRIVPY---PLQML 89

  Fly    75 VDHDELFNRVIGMQKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWL 139
            ..|...|                 ..|.|..|.:.:.:||.::.:.|......|:|.:. |...:
plant    90 KTHGRTF-----------------FTWFGPIPTITIMDPEQIKEVFNKVYDFQKAHTFP-LGRLI 136

  Fly   140 GEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLA---RKLAVEVGSEA-FNLFPYV 200
            ..||::....||...|:|:.||||.:.:.:.:..|::..:.:.   .||..:..|.. .:::|::
plant   137 AAGLVSYDGDKWTKHRRIINPAFHLEKIKNMVPAFHQSCSEIVGEWDKLVTDKQSSCEVDIWPWL 201

  Fly   201 TLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSY 265
            ...|.|::..||.|     .|..|.:.:..       :|:..|::.:|: |..::...|:...:.
plant   202 VSMTADVISRTAFG-----SSYKEGQRIFE-------LQAELAQLIIQA-FRKAIIPGYRYFPTK 253

  Fly   266 IN------------TLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLI 318
            .|            .|.|..|..:|.|:|             ..||.  ||:        |.:|:
plant   254 GNRRMKAAAREIKFILRGIVNKRLRAREA-------------GEAPS--DDL--------LGILL 295

  Fly   319 DAS---KEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDK 380
            :::   .:|..:|.|::.||...|.|.|.:||:..:.||:.||..|.::|.|..||:..:|| ||
plant   296 ESNLGQTKGNGMSTEELMEECKLFYFAGQETTTVLLVWTMVLLSQHQDWQARAREEVKQVFG-DK 359

  Fly   381 ETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPR 445
            |..|  :.|..::.:...:.:.|||:|.|..:.|.:.:::.:|...:|.|.|..:....:.|:..
plant   360 EPDA--EGLNQLKVMTMILYEVLRLYPPVVQLTRAIHKEMQLGDLTLPGGVQISLPILLIQRDRE 422

  Fly   446 VFPKPE-QFNPDNFLPE-NCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIE 505
            ::.... :|.||.|... :.|.::..::.||:.|||.||||.||:||.|..::.:|||:..|
plant   423 LWGNDAGEFKPDRFKDGLSKATKNQVSFFPFAWGPRICIGQNFALLEAKMAMTLILRKFSFE 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	114/468 (24%)
CYP72A13	NP_188084.1	p450	24..512	CDD:299894	126/517 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860