DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4c3 and BAS1

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	567	Identity:	148/567 - (26%)
Similarity:	254/567 - (44%)	Gaps:	107/567 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSKVITSLMAESILLSKVGQVISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEK--IPGPAAM 64
            ||..|..::..|::||.|  ::.|.|             |:.:..|  ::.::..|  |.||...
plant     6 SSWFIPKVLVLSVILSLV--IVKGMS-------------LLWWRPR--KIEEHFSKQGIRGPPYH 53

  Fly    65 PFLGNAIE------------MNVDHDELFNRVIGMQKLWGTRIGIN-RVWQGTAPRVLLFEPETV 116
            .|:||..|            |...|: :..||:.....|....|.. .||.|...|:.:.:|:.:
plant    54 FFIGNVKELVGMMLKASSHPMPFSHN-ILPRVLSFYHHWRKIYGATFLVWFGPTFRLTVADPDLI 117

  Fly   117 EPILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFK--------ILDDFIDV 173
            ..|.:..:|..|:..:..:....|:|||:....||...|||::|.||.:        :|....|:
plant   118 REIFSKSEFYEKNEAHPLVKQLEGDGLLSLKGEKWAHHRKIISPTFHMENLKLLVPVVLKSVTDM 182

  Fly   174 FNEQSAVLARKLAVEVGSEAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIV 238
            .::.|..|:....|||     :::.:..:.|.|::..||.|        |..|..:||:.:
plant   183 VDKWSDKLSENGEVEV-----DVYEWFQILTEDVISRTAFG--------SSYEDGRAVFRL---- 230

  Fly   239 QSRQ--------AKIWLQSDFIFSLTA---EYKLHQSYINTLHGFSNMVIRERKAELAILQENNN 292
            |::|        .|:::.....|....   .:||.:..              ||:.|.:::....
plant   231 QAQQMLLCAEAFQKVFIPGYRFFPTRGNLKSWKLDKEI--------------RKSLLKLIERRRQ 281

  Fly   293 NNNNNAPDAYDDVGKK-KRLAFLDL--LIDASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWT 354
            |       |.|..|:: |..|..||  |:..:|..||   :||.||..:|.|.|..|||..::||
plant   282 N-------AIDGEGEECKEPAAKDLLGLMIQAKNVTV---QDIVEECKSFFFAGKQTTSNLLTWT 336

  Fly   355 LFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGED 419
            ..||..|||:|.:..:|:..:.| .::.| |..:::.::.|...:.:||||:|.:....|....|
plant   337 TILLSMHPEWQAKARDEVLRVCG-SRDVP-TKDHVVKLKTLSMILNESLRLYPPIVATIRRAKSD 399

  Fly   420 VNIGGKIVPAGTQAIIMTYALHRNPRVFPKP-EQFNPDNF---LPENCAGRHPFAYIPFSAGPRN 480
            |.:||..:|.||:.:|...|:|.:..::... .:|||..|   :|.  |.:||..:|||..|.|.
plant   400 VKLGGYKIPCGTELLIPIIAVHHDQAIWGNDVNEFNPARFADGVPR--AAKHPVGFIPFGLGVRT 462

  Fly   481 CIGQKFAILEEKAVISTVLRKYKIE-AVDRREDLTLLGELILRPKDG 526
            ||||..|||:.|..::.:::::... |...:...|:|  ::|.|:.|
plant   463 CIGQNLAILQAKLTLAVMIQRFTFHLAPTYQHAPTVL--MLLYPQHG 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	135/508 (27%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	125/470 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860