DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and CYP96A1

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_179899.1	Gene:	CYP96A1 / 816850	AraportID:	AT2G23180	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	553	Identity:	122/553 - (22%)
Similarity:	236/553 - (42%)	Gaps:	108/553 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 FLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVIGMQKLWGTRIG 96
            ||.|   .||:.....||.|..:          ||||....:.|:...:::.|..:.:.......
plant    18 FLYG---YFLISKKPHRSFLTNW----------PFLGMLPGLLVEIPRVYDFVTELLEASNLTYP 69

  Fly    97 INRVWQGTAPRVLLFEPETVEPILNSQKFVN--KSHDYDYLHPWLGEGLLTSTDRKWHSRRKI-- 157
            ......|....::..:|..:..|::| .|.|  |..::..:...||:|:..:....|...||.
plant    70 FKGPCFGGLDMLITVDPANIHHIMSS-NFANYPKGTEFKKIFDVLGDGIFNADSELWKDLRKSAQ 133

  Fly   158 -----------------------LTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNLFPY 199
                                   |.|...:               |..:|..|:: .:.|..|.:
plant   134 SMMTHQDFQRFTLRTIMSKLEKGLVPLLDY---------------VAEKKQVVDL-QDVFQRFTF 182

  Fly   200 VT---LCT-LDIVC-ETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAK---IWLQSDFIFSLT 256
            .|   |.| :|..| .|.|.:..:|::..|:|  :|::       .|..|   :|....|| ...
plant   183 DTSFVLATGVDPGCLSTEMPQIEFARALDEAE--EAIF-------FRHVKPEIVWKMQRFI-GFG 237

  Fly   257 AEYKLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDAS 321
            .|.|:.::: :|.....:..|..::.|:.....|.::::.:....|.:|         |.:...:
plant   238 DELKMKKAH-STFDRVCSKCIASKRDEITNGVINIDSSSKDLLMCYMNV---------DTICHTT 292

  Fly   322 KEGTVLSNED--IREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPA 384
            |...:..::|  :|:.:.:||..|.||||:|::|..:||..:|:...::.:|:::     :.:|.
plant   293 KYKLLNPSDDKFLRDMILSFMLAGRDTTSSALTWFFWLLSKNPKAITKIRQEINT-----QLSPR 352

  Fly   385 T-------MKNLMDMRYLECCIKDSLRLFPSVPMMARM-VGEDVNIGGKIVPAGTQAIIMTYALH 441
            |       .:.|..:.|:...:.::|||:|.||...:. ...||...|..|.|.::.:...|:|.
plant   353 TNDFDSFNAQELNKLVYVHGALCEALRLYPPVPFQHKSPTKSDVLPSGHRVDASSKIVFCLYSLG 417

  Fly   442 RNPRVFPK-PEQFNPDNFLPENCAGR--H--PFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRK 501
            |...|:.: ..:|.|:.::.|  :||  |  .|.::.|:||||.|:|::.|:.:.|.|...:::.
plant   418 RMKSVWGEDASEFKPERWISE--SGRLIHVPSFKFLSFNAGPRTCLGKEVAMTQMKTVAVKIIQN 480

  Fly   502 YKIEAVDRREDLTLLGELILRPKDGLRVKITPR 534
            |:|:.|:..: :..:..:||..|.||:|.:|.|
plant   481 YEIKVVEGHK-IEPVPSIILHMKHGLKVTVTKR 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	112/521 (21%)
CYP96A1	NP_179899.1	p450	1..512	CDD:299894	121/551 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1194
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920