Protein Alignment Cyp4c3 and cyp4v2.2

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001072667.1
• Gene: cyp4v2.2 / 780124
• XenbaseID: XB-GENE-977085
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 246/509 - (48%)
• Similarity: 349/509 - (68%)
• Gaps: 12/509 - (2%)

  Fly    29 ITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAA-MPFLGNAIEMNVDHDELFNRVIGMQKLWG 92
            :|:..| |||..|..|.::|    :.::.||||.. .|.:|:|:.:..:..:.|.::....:.:.
 Frog    20 LTLLAL-SILPALQDYVRKR----RILKPIPGPGPNYPLIGDALFLKNNGGDFFLQICEYTESYR 79

  Fly    93 TRIGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWHSRRKI 157
            .: .:.:||.||.|.::::..:||||:|:|.|.::|:..|.:||||||:||||||..||.||||:
 Frog    80 LQ-PLLKVWIGTIPFIVVYHADTVEPVLSSSKHMDKAFLYKFLHPWLGKGLLTSTGEKWRSRRKM 143

  Fly   158 LTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNLFPYVTLCTLDIVCETAMGRRIYAQSN 222
            :||.|||.||.:|::|.||||.:|..||...|..|:|:.|..||||.|||:.||||||:|.||||
 Frog   144 ITPTFHFAILSEFLEVMNEQSKILVEKLQTHVDGESFDCFMDVTLCALDIISETAMGRKIQAQSN 208

  Fly   223 SESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLHGFSNMVIRERKAELAIL 287
            .:||||:|:|.:..|:|.||...||..||:::...:.|.|...:..||.|::..|.||..||..:
 Frog   209 RDSEYVQAIYKMSDIIQRRQKMPWLWLDFLYAHLRDGKEHDKNLKILHSFTDKAILERAEELKKM 273

  Fly   288 QENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKE-GTVLSNEDIREEVDTFMFEGHDTTSAAI 351
            .|....:.::.|::..   .|||.||||:|:.|:.: |..:|..|||||||||||||||||:||:
 Frog   274 GEQKKEHCDSDPESDK---PKKRSAFLDMLLMATDDAGNKMSYMDIREEVDTFMFEGHDTTAAAL 335

  Fly   352 SWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMV 416
            :|:|||||.|||.|.:|.:|||.:|| ..:.|.||.:|..:||||..||:|||::||||:..|.|
 Frog   336 NWSLFLLGSHPEAQRQVHKELDEVFG-KSDRPVTMDDLKKLRYLEAVIKESLRIYPSVPLFGRTV 399

  Fly   417 GEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNC 481
            .||.:|.|..||.|...:|:.|||||:|..||:||:|.|:.|.|||.:||:|:||||||||.|||
 Frog   400 TEDCSIRGFHVPKGVNVVIIPYALHRDPEYFPEPEEFRPERFFPENASGRNPYAYIPFSAGLRNC 464

  Fly   482 IGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVKITPRD 535
            |||:||::|||.|:|::||.|.:||..:||:|.|||||||||:||:.:|:..|:
 Frog   465 IGQRFALMEEKVVLSSILRNYWVEASQKREELCLLGELILRPQDGMWIKLKNRE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	235/473 (50%)
cyp4v2.2	NP_001072667.1	p450	45..509	CDD:365848	233/468 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	467	1.000	Domainoid score	I460
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H133054
Inparanoid	1	1.050	478	1.000	Inparanoid score	I1439
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		oto103614
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4308
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090