Protein Alignment Cyp4c3 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001038763.1
• Gene: cyp46a1.3 / 692332
• ZFINID: ZDB-GENE-060519-40
• Length: 491
• Species: Danio rerio
• Alignment Length: 485
• Identity: 129/485 - (26%)
• Similarity: 213/485 - (43%)
• Gaps: 72/485 - (14%)

  Fly    32 FLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVIGMQK------- 89
            :||.::.:..:.|.....::.:..:.||||....||       :.|....|||...::
Zfish    12 YLLSAVFVVFLAYCLYIHQVHQKYDHIPGPPRDNFL-------LGHIPTINRVTKSERHMNDLLL 69

  Fly    90 LWGTRIGINRVWQGTAPRVLLFE---PETVEPILNSQKFVNKSHDYDYL-----HPWLGEGLLTS 146
            :|..:.|  .|::..:...::..   ||..:.|:.|.|::.....|..|     ..:||.||:|:
Zfish    70 IWAEKYG--PVYRLNSFHYVIINVHCPEATKTIMMSPKYLKDPFIYKRLFGLFGKRFLGYGLVTA 132

  Fly   147 TDRK-WHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNLFP-----YVTLCTL 205
            ||.. |:.:|:|:.|||....|...|..|||.|..|..||.    ..|.|..|     .|...||
Zfish   133 TDHDIWYRQRRIMDPAFSSSYLRGLISTFNEMSERLMDKLE----EMAINKTPAVMHDLVNCVTL 193

  Fly   206 DIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIW-LQSDFIFSLTAEYKLHQSYINTL 269
            ||:|:.|.|..:.....:::.:.:|      |.|..|..:. |:..|.......:|
Zfish   194 DIICKVAFGVDLNLFKQTDNPFQQA------IEQCLQGMVLDLRDPFCKFFPKNWK--------- 243

  Fly   270 HGFSNMVIRERKAELAILQENNN---NNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGTVLSNED 331
                  .|:|.|....:|::...   .|...|.:..:||...    .|..::..:||..|.:.:|
Zfish   244 ------AIQETKGATVLLRKTGEQWIQNRKTAVEIGEDVPND----ILTQILKTAKEEKVNNTKD 298

  Fly   332 IREEVD---TFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMR 393
            ..:.:|   ||...|.:||:..:|:.:..||.|||..:|...|:|.:.|..::  .:.::|....
Zfish   299 HEQMLDNFVTFFIAGQETTANQLSFAIMELGRHPEIYKRAKAEVDEVLGTKRD--ISYEDLGKFT 361

  Fly   394 YLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNF 458
            ||...:|::|||:|:.|...|.:.||:.|.|..:|.|...|..:|...|..:.|..|.:|:|:.|
Zfish   362 YLSQVLKETLRLYPTAPGTNRWLHEDMVINGIKIPGGISVIFSSYVAQRLEKHFKDPLKFDPERF 426

  Fly   459 LPENCAGRHP-FAYIPFSAGPRNCIGQKFA 487
               |.....| :.|.|||.|||:|:||.|:
Zfish   427 ---NVNAPKPYYCYYPFSLGPRSCLGQVFS 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	125/458 (27%)
cyp46a1.3	NP_001038763.1	p450	39..452	CDD:278495	124/455 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820