Protein Alignment Cyp4c3 and Cyp4f37

DIOPT Version :10

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_038935973.1
• Gene: Cyp4f37 / 691312
• RGDID: 1585102
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 187/531 - (35%)
• Similarity: 282/531 - (53%)
• Gaps: 62/531 - (11%)

  Fly    32 FLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGN--AIEMNVDHDELFNRVIGMQKLWGTR 94
            ::|..||.:...:.:..|||..:.:   .|....|||:  .|:.|.:         |||.:  |.
  Rat    29 WILARILAWTYSFCENCSRLRCFPQ---SPKRNWFLGHLGVIQSNEE---------GMQLV--TE 79

  Fly    95 IG-----INRVWQG-TAPRVLLFEPETVEPILNSQKFVNKSHDYDYLH---PWLGEGLLTSTDRK 150
            :|     ::.:|.| .:|.:.|.:|..|.|:|.:...| ...|..:||   ||||:||..|:..|
  Rat    80 MGQTFRDVHLIWLGPVSPVLRLVDPAFVAPLLQAPALV-APKDPTFLHFLKPWLGDGLFLSSGDK 143

  Fly   151 WHSRRKILTPAFHFKILDDFIDVFNEQSAVLARK---LAVEVGSEAFNLFPYVTLCTLDIVCETA 212
            |...|::|||||||.||..::..||:...::..|   |.:| ||....:|..::|.|||.:.:..
  Rat   144 WSRHRRLLTPAFHFDILKPYVKTFNQSVNIMHAKWKHLCLE-GSARLEMFENISLMTLDSLQKCL 207

  Fly   213 MGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLHGFSNMVI 277
            .|.....| .|.|||:.|...:.|:.:.|..|::|..||::..||:.:..:...:.:|.|::.||
  Rat   208 FGFDSNCQ-ESPSEYISATLELSSLTRKRSYKLFLYLDFLYYRTADGQRFRKACDLVHSFTDAVI 271

  Fly   278 RERKAELA------ILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKE-GTVLSNEDIREE 335
            |||:..|:      .|:....:             |.|.|.|:|:|:.|..| |..||:||||.|
  Rat   272 RERRRLLSSQGVDEFLESKTKS-------------KSKTLDFIDVLLLAKDEHGKELSDEDIRAE 323

  Fly   336 VDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIK 400
            .|||||.|||||::|:||.|:.|..|||||||..:|:..:..|.:.......:|..:.:|..|||
  Rat   324 ADTFMFGGHDTTASALSWILYNLASHPEYQERCRQEVWELLRDREPEEIEWDDLAQLPFLTMCIK 388

  Fly   401 DSLRLF-PSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCA 464
            :||||. |:|.::.|...:.|...|:::|.|...:|..:.:|.||.|:|.||.::|..|.|||..
  Rat   389 ESLRLHPPAVDLLRRCTQDIVLPDGRVIPKGNICVISIFGIHHNPSVWPDPEVYDPFRFDPENRQ 453

  Fly   465 GRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVD---RREDLTLLGELILRPKDG 526
            .|.|.::|||||||||||||.||:.|.|..:...|.:::....|   ||:.     |||||.:.|
  Rat   454 KRSPLSFIPFSAGPRNCIGQTFAMNEVKVAVGLTLLRFRFLPDDKEPRRKP-----ELILRAEGG 513

  Fly   527 --LRVKITPRD 535
              |||::..||
  Rat   514 LWLRVELLSRD 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	167/457 (37%)
Cyp4f37	XP_038935973.1	CYP4F	74..517	CDD:410772	169/465 (36%)