Protein Alignment Cyp4c3 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 535
• Identity: 143/535 - (26%)
• Similarity: 259/535 - (48%)
• Gaps: 82/535 - (15%)

  Fly    31 VFLLGSILIFLVVYNKRRSRLVKYI----EKIPGPAAMP----FLGNA---IEMNVDHDELFNRV 84
            :.||..|||..:::    |..:.||    :.||||   |    |||::   :.:..::..:::..
 Frog    12 LLLLALILICFLLF----SGYIHYIHMKYDHIPGP---PRDSFFLGHSPTMLRLMKNNLLMYDHF 69

  Fly    85 IGMQKLWG--TRI-GINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLH-----PWLGE 141
            :|..:.:|  .|| |::||      .:|:..||.|:.:|.|.|: :|...||.:.     .::|:
 Frog    70 LGWVQKYGPVVRINGLHRV------IILVVSPEAVKELLMSPKY-SKDKFYDVIANMFGVRFMGK 127

  Fly   142 GLLTSTD-RKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEV-GSEAFNLFPYVTLCT 204
            ||:|..| ..||.:|:|:.|||....|...:..|||::..|..||..:. |.....:...::..|
 Frog   128 GLVTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKADGKCEIKMHDMLSRLT 192

  Fly   205 LDIVCETAMGRRIYAQSNSESEYVKAV-YGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINT 268
            ||::.:.|.|..:.:.::..:.:.||: ..:..||:.|...:            .|.|.:
 Frog   193 LDVIGKVAFGMELNSLNDDLTPFPKAISLVMKGIVEMRNPMV------------RYSLAK----- 240

  Fly   269 LHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGTVLSNEDIR 333
             .||    ||:.:..:.:|::..............| |:       ::.:|...:  :|....:.
 Frog   241 -RGF----IRKVQESIRLLRQTGKECIERRQKQIQD-GE-------EIPVDILTQ--ILKGAAME 290

  Fly   334 EEVD---------TFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNL 389
            ||.|         ||...|.:||:..:|:.:..||.:||..|:...|:|.:.|..::  ...::|
 Frog   291 EECDPEILLDNFVTFFIAGQETTANQLSFVVMELGRNPEILEKAQAEIDEVIGSKRD--IEYEDL 353

  Fly   390 MDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFN 454
            ..::||...:|::|||:|:.|..:|.:.||:.|.|..||.....::.:|.:.|..:.:..|..||
 Frog   354 GKLQYLSQVLKETLRLYPTAPGTSRGLTEDMVIDGVKVPENVTIMLNSYIMGRMEQYYSDPLTFN 418

  Fly   455 PDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGEL 519
            ||.|.|:  |.:..::|.|||.|||:||||.|:.:|.|.|::.:|::|:.|..: .:...:|...
 Frog   419 PDRFSPD--APKPYYSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYEFELAE-GQSFKILDTG 480

  Fly   520 ILRPKDGLRVKITPR 534
            .|||.||:..::.||
 Frog   481 TLRPLDGVICRLRPR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	132/498 (27%)
cyp46a1.3	NP_001027517.1	p450	40..491	CDD:306555	132/497 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910