Protein Alignment Cyp4c3 and Cyp3a25

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 542
• Identity: 143/542 - (26%)
• Similarity: 253/542 - (46%)
• Gaps: 73/542 - (13%)

  Fly    21 QVISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVI 85
            ::|...|..|..||.:.|:...:|......|.|.: .||||..:|.||.          :||...
Mouse     2 ELIPNLSIETWVLLVTSLVLFYIYGTYSHGLFKKL-GIPGPKPLPLLGT----------IFNYYD 55

  Fly    86 GM-----------QKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQ---KFVNKSHDYDYLH 136
            ||           .|:||       .::|..|.:.:.:||.::.:|..:   .|.|:.    :..
Mouse    56 GMWKFDEDCYKKYGKIWG-------FYEGPQPILAIMDPEIIKIVLVKECYSVFTNRR----FFG 109

  Fly   137 P--WLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKL-AVEVGSEAFNLFP 198
            |  ::.:.:..|.|.:|...|.:|:|.|....|.:...:..:...:|.|.| ..|...|..::..
Mouse   110 PVGFMKKAITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKD 174

  Fly   199 YVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFS-LTAEYKLH 262
            .....::|::..|:.|..:.:.:|.:..:|:..   ..|::.:....:|.|..:|. ||..|::.
Mouse   175 IFGAYSMDVITGTSFGVNVDSLNNPQDPFVQKA---KKILKFKIFDPFLLSIILFPFLTPIYEML 236

  Fly   263 QSYI---NTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLID----- 319
            ...|   ::::.|...|.|.:|..||..|:|                   |:.||.|:::
Mouse   237 NFSIFPRDSMNFFKKFVKRMKKERLASNQKN-------------------RVDFLQLMMNTQNSK 282

  Fly   320 ASKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPA 384
            ..:....||:.::..:...|:|.|:|.||.:||..::.|..||:.|:::.:|:|...  ..:.|.
Mouse   283 GQESQKALSDLEMAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTL--PNKAPV 345

  Fly   385 TMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPK 449
            |...||||.||:..:.:||||:|....:.|:..:||.|.|..:|.||..:|..|.|||||..:|:
Mouse   346 TYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPE 410

  Fly   450 PEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRRE-DL 513
            |::|.|:.|..||.....|:.|:||..|||||||.:||::..|..:..||:.:.::..:..: .|
Mouse   411 PQEFCPERFSKENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPL 475

  Fly   514 TLLGELILRPKDGLRVKITPRD 535
            .:..|.|.:|:..:.:|:..||
Mouse   476 KISREPIFQPEKPIILKVVSRD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	130/498 (26%)
Cyp3a25	NP_062766.2	p450	39..493	CDD:278495	130/498 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810