Protein Alignment Cyp4c3 and cyp3a65

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001032515.1
• Gene: cyp3a65 / 553969
• ZFINID: ZDB-GENE-050604-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 548
• Identity: 141/548 - (25%)
• Similarity: 250/548 - (45%)
• Gaps: 87/548 - (15%)

  Fly    26 YSPITVFLLGSILIFLVVYNKRRSRLVKYIEK--IPGPAAMPFLGNAIE-------MNVDHDELF 81
            :|..|..||..:...||:|.....|   |.:|  ||||.|:||.|..:.       .::|..|.:
Zfish     3 FSAETWTLLAFLAALLVIYGSWPHR---YFKKLGIPGPKAIPFFGTMLRYKDGFHVFDMDCFEKY 64

  Fly    82 NRVIGMQKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQ---KFVNKSHDYDYLHPWLGEGL 143
            .|:      ||       ::.|..|.:.:.:...::.:|..:   .|.|:.:  ..|:..|.:.:
Zfish    65 GRI------WG-------IYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRN--FRLNGALYDAV 114

  Fly   144 LTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLA-VEVGSEAFNLFPYVTLCTLDI 207
            ..:.|..|...|.:|:|:|....|.:...:..:.|.:|...:. .....|:.::..:....::|:
Zfish   115 SIAEDDDWRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAKRGESADIKEFFGAYSMDV 179

  Fly   208 VCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDF---IFSLTAEYKLHQSYINTL 269
            |..||....|.:.:|.:..:|..:            |..|:.|.   :|.|.|.:.
Zfish   180 VTSTAFSVDIDSLNNPKDPFVTNI------------KKMLKFDLLNPLFLLIAFFP--------- 223

  Fly   270 HGFSNMVIRERKAEL----------AILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDA---- 320
              |...|:.:....|          |.||:..::.:.... |.|:.  |||:.||.|::|:
Zfish   224 --FMAPVLEKMDFALFPTSVTDFFYAALQKIKSDRDTKTV-AKDNT--KKRVDFLQLMVDSQTGV 283

  Fly   321 --------SKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFG 377
                    :::|  ||:.:|..:...|:|.|::|:|:.:|:..:.|..:||..:::.||:|..|
Zfish   284 KHKSDGEHTEKG--LSDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETF- 345

  Fly   378 DDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHR 442
             ..:.|...:.||.|.||:..:.:||||||....:.|:..:.|.|.|.::|.....::.||||||
Zfish   346 -PNQAPVDYETLMSMDYLDAALSESLRLFPVAARLERVCKKTVEINGLLIPKDLVVMVPTYALHR 409

  Fly   443 NPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAV 507
            :|..:.:||.|.|:.|...|.....|:.|:||..|||||||.:||.:..|..|..:|:::.:...
Zfish   410 DPDYWSEPESFKPERFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVC 474

  Fly   508 DRREDLTLLG-ELILRPKDGLRVKITPR 534
            |..:....|| ..:|.|||.:::|:.||
Zfish   475 DETQVPLELGFNGLLSPKDPIKLKLQPR 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	127/508 (25%)
cyp3a65	NP_001032515.1	p450	35..499	CDD:278495	127/508 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810