Protein Alignment Cyp4c3 and cyp3c3

DIOPT Version :10

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001007401.2
• Gene: cyp3c3 / 492759
• ZFINID: ZDB-GENE-041114-102
• Length: 503
• Species: Danio rerio
• Alignment Length: 551
• Identity: 146/551 - (26%)
• Similarity: 244/551 - (44%)
• Gaps: 118/551 - (21%)

  Fly    38 LIFLVVYNKRRSRLVKY-------IEK--IPGPAAMPFLGNAIEMNVDHDELFNRVIGMQ----- 88
            |:|||:     :.|..|       .:|  ||||...||.|..:...   ...||  ..|:
Zfish    13 LVFLVI-----TLLYMYGVWPHGFFKKLGIPGPRPWPFFGTFLSYT---KGFFN--FDMECAKKY 67

  Fly    89 -KLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQ---KFVNKSH-DYDYLHPWLGEGLLTSTD 148
             |:||       ::.|..|.:::.:.|.::.|:..:   .|.|:.. :.|...| |.:|:....|
Zfish    68 GKVWG-------IYDGRLPILMVTDLEMIKTIMVKECYSTFTNRREVNVDLAGP-LADGISAVKD 124

  Fly   149 RKWHSRRKILTPAFH-------FKILDDFIDVF--------NEQSAVLARKLAVEVGSEAFNLFP 198
            .:|...|..|:|.|.       |.|.....|.|        :||...:...:|           |
Zfish   125 ERWKRIRGTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKRDHEQPVKIKEVVA-----------P 178

  Fly   199 YVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQ 263
            |    :||:|..::....|.:.:|.:..:|..:...        .|..|.|..|..||    |..
Zfish   179 Y----SLDVVTSSSFSVDIDSINNPDDPFVTNIKNF--------LKFSLFSPLILFLT----LFP 227

  Fly   264 SYINTL-----HGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLI----- 318
            |..|.|     ..||..::......|..:::.:.::|.             |:.||.|:|
Zfish   228 SIANLLGKMGISVFSRSIMNFFYTALRKIKDEHKDSNG-------------RVDFLRLMIQNQIP 279

  Fly   319 -DASKEGTV------LSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIF 376
             |.:|:.|.      |::.:|..:...|:..|::|||..:|:.|..|..:|:..|::|||:|..|
Zfish   280 DDQAKDTTSEQPVKGLTDHEILSQSFIFILGGYETTSTTLSFLLHNLATNPDCLEKLVEEIDKNF 344

  Fly   377 GDDKETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALH 441
            ..|  ||.:...||.|.|||..|.:|:||.|:.|.:.|:..:.|.:.|..:|..|...|.||.|:
Zfish   345 PLD--TPISYDALMKMDYLEMSINESMRLLPTAPRLERVCKKTVELNGITIPKDTLVAIPTYVLN 407

  Fly   442 RNPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEA 506
            |:|:::..|::|.|:.|.|||.:....:|::||..|||||||.:||::..|.::..:|:.:.:|.
Zfish   408 RDPQLWDSPQEFRPERFSPENKSEFLQYAFMPFGLGPRNCIGMRFALMIVKLLVVKLLQNFSLET 472

  Fly   507 VDRRE---DLTLLGELILRPKDGLRVKITPR 534
            ....:   :||    .:.:||..:.:|:|||
Zfish   473 CKETQIPLELT----PVFQPKVPITLKLTPR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	122/471 (26%)
cyp3c3	NP_001007401.2	cytochrome_P450	66..495	CDD:477761	125/482 (26%)