Protein Alignment Cyp4c3 and Cyp4e1

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 190/546 - (34%)
• Similarity: 285/546 - (52%)
• Gaps: 65/546 - (11%)

  Fly    29 ITVFLLGSILIFLVVYNK----RRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVIGMQK 89
            :..||  ::.:|||.|.:    ||.|:   :.|..||:.:|.:|||.:|.....|:.||..|
  Fly     5 LCAFL--ALPLFLVTYFELGLLRRKRM---LNKFQGPSMLPLVGNAHQMGNTPTEILNRFFG--- 61

  Fly    90 LWGTRIGIN--RVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWH 152
             |....|.:  |.|.|....:::..|:.:|.||:||..::||..||..|||||.||||||..|||
  Fly    62 -WWHEYGKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWH 125

  Fly   153 SRRKILTPAFHFKILDDFIDVFNEQSAVLARKL-AVEVGSEAFNLFPYVTLCTLDIVCETAMGRR 216
            ..||::||||||.||.||.:|.||.|.....:| .|..|...|:........|||::|:||||..
  Fly   126 KHRKMITPAFHFNILQDFHEVMNENSTKFIDQLKKVADGGNIFDFQEEAHYLTLDVICDTAMGVS 190

  Fly   217 IYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLHGFSNMVIRE-- 279
            |.|..|..|..|:|...|...::.|....|.::.::|....||..:...:.||..|:|.:|.:
  Fly   191 INAMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFAPEYPEYSKTLKTLQDFTNEIIAKRI 255

  Fly   280 --RKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGTVLSNEDIREEVDTFMFE 342
              ||:.|.:             ....|...:|::||||.|:.:..:|..|:::::.|||.|||||
  Fly   256 EVRKSGLEV-------------GIKADEFSRKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFE 307

  Fly   343 GHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFG-DDKETPATMKNLMDMRYLECCIKDSLRLF 406
            |||||::.:.:.::||..||:.||::..|...:.| ......||.:.:..|::|:..||::.||:
  Fly   308 GHDTTTSGVGFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRDATFQEISTMKHLDLFIKEAQRLY 372

  Fly   407 PSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPFAY 471
            ||||.:.|...:|..|.|.|||.||...:....|..|.|||..|.:|.|:.|..|...   ||.|
  Fly   373 PSVPFIGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKPG---PFEY 434

  Fly   472 IPFSAGPRNCIGQKFAILEEKAVISTVLRKYKI----------------------------EAVD 508
            :|||||||||||||||:||.|.|:|.::|.:::                            :|.:
  Fly   435 VPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHN 499

  Fly   509 RREDLTLLGELILRPKDGLRVKITPR 534
            .:.|..|...:.|:.::||.:::..|
  Fly   500 HKYDPILSASMTLKSENGLHLRMKQR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	179/507 (35%)
Cyp4e1	NP_524771.1	p450	34..469	CDD:278495	173/454 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460451
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	11	10.800