DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and Cyp309a2

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_608689.2	Gene:	Cyp309a2 / 33439	FlyBaseID:	FBgn0041337	Length:	538	Species:	Drosophila melanogaster

Alignment Length:	488	Identity:	108/488 - (22%)
Similarity:	193/488 - (39%)	Gaps:	107/488 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 NRVIGMQKLWGTRIGINR---VWQGTAPRVLLFEPETVEPILNS----------QKFVN--KSHD 131
            |.|..:||::....|.:|   |:....|::|:.:||....:|.|          ..::.  |...
  Fly    87 NLVFDVQKIYDKYKGKHRAVGVFVTRQPQILVLDPELAHEVLVSNFRCYKDSLQSSYLRHAKWDK 151

  Fly   132 YDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNL 196
            |..|:|:...|      :.|...|...........|....:::.:...:|...:..:| :|..|:
  Fly   152 YARLNPFWASG------QSWRRLRTDAQAGISGSRLRQAYNIWEQGGQMLTEYMTQQV-AEKNNI 209

  Fly   197 FPYVTLC---TLDIVCETAMG------RRIYAQSNSESE----------YVKAVYGIGSIVQSRQ 242
            .....||   |..::.:...|      .|...|.|...|          |:..:: :.:|| :..
  Fly   210 LETRDLCFRYTAHVMADFIWGIDAGTLTRPMEQPNKVQEMASKWTSYAFYMLTLF-MATIV-APC 272

  Fly   243 AKIWLQSDFIFSLTAEYKLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGK 307
            :::.|:..|....|.|:            |||:.  :...||.:                 ..|.
  Fly   273 SRLLLRFRFYPKETDEF------------FSNLT--KESIELRL-----------------KAGD 306

  Fly   308 KKRLAFLDLLIDA--SKEGTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVE 370
            ..|..:|..|:..  .|:.|   ::|:.....|.|.:|:||:..|:...|:.|..:|..|:::..
  Fly   307 STRTDYLSHLLQLRDQKQAT---HDDLVGHALTVMLDGYDTSGTALLHALYYLAENPAVQQKLRV 368

  Fly   371 ELDSIFGDDKETPATMKNLMDMRYLECCIKDSLRL------------FPSVPMMARMVGEDVNIG 423
            |:.|....:|.  ...:.|..::|||..|.:||||            .|:|..::.....||.:|
  Fly   369 EILSCMASEKS--LDFEKLSSLQYLEQVIYESLRLSSLIPQYTKVCTLPTVIRLSESKSLDVEVG 431

  Fly   424 GKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPF---AYIPFSAGPRNCIGQK 485
            ..|       :|..|..|.:.:.||:||.|.|:.|  :|.|.:...   .::|||.|||.|:|..
  Fly   432 MTI-------MIPNYQFHHDKQYFPEPEAFKPERF--DNGAYQELMRKGIFLPFSDGPRICMGVP 487

  Fly   486 FAILEEKAVISTVLRKYKIEAVDRREDLTLLGE 518
            .|:|..|:.:..:|..:::  |..|:.|...|:
  Fly   488 LAMLTLKSALVHILSNFQV--VRGRDRLIPKGD 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	108/488 (22%)
Cyp309a2	NP_608689.2	p450	70..526	CDD:299894	108/488 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010