Protein Alignment Cyp4c3 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 172/521 - (33%)
• Similarity: 277/521 - (53%)
• Gaps: 46/521 - (8%)

  Fly    29 ITVFLLGSIL--IFLVVYNK-----RRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVIG 86
            ::.|..|:.|  :|||::..     ||..|:|.:||.|...:....|:.::     |..|.:|:
  Rat    15 VSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHDLK-----DREFQQVL- 73

  Fly    87 MQKLWGTRI-GINRVW-QGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWL----GEGLLT 145
               .|..:. |....| .|:..||||::|:.|:.:| .:.....|..|.:|.||:    |.|||.
  Rat    74 ---TWVEKFPGACLQWLSGSKTRVLLYDPDYVKVVL-GRSDPKASGIYQFLAPWIVSGTGYGLLL 134

  Fly   146 STDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKL-AVEVGSEAFNLFPYVTLCTLDIVC 209
            ...:||....::||||||:.||..::.:..:..:::..|. .::.......:|.||:|.|||.|.
  Rat   135 LNGKKWFQHWRMLTPAFHYGILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVM 199

  Fly   210 ETAMGRR--IYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLHGF 272
            :.|...:  :....||.| |.|||..:.::...|....:..:..|::::::.:|.:......|..
  Rat   200 KCAFSHQGSVQLDVNSRS-YTKAVEDLNNLTFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEH 263

  Fly   273 SNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKE-GTVLSNEDIREEV 336
            ::.||:.|||:|...:|            .....||:.|.|||:|:.|..| |..||:||:|.||
  Rat   264 TDGVIKMRKAQLQNEEE------------LQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEV 316

  Fly   337 DTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMKNLMDMRYLECCIKD 401
            |||||||||||::.|||..:.|..|||:|||..||:.||.||.  |..|..:|..:.|...|||:
  Rat   317 DTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDG--TSVTWDHLDQISYTTMCIKE 379

  Fly   402 SLRLFPSVPMMARMVGEDVNI-GGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAG 465
            :|||:|.||.::|.:...|.. .|:.:|.|....|:.|.||.||..:|.|:.|:|..|.|:  :.
  Rat   380 ALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYWPNPKVFDPSRFSPD--SP 442

  Fly   466 RHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDGLRVK 530
            ||..||:|||.|.|||||::||:.|.|..::..|.::::.....|..:. :..|:|:.|:|:.::
  Rat   443 RHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVP-MARLVLKSKNGIHLR 506

  Fly   531 I 531
            :
  Rat   507 L 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	154/442 (35%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	157/459 (34%)