Protein Alignment Cyp4c3 and Cyp26b1

DIOPT Version :10

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_780684.1
• Gene: Cyp26b1 / 232174
• MGIID: 2176159
• Length: 512
• Species: Mus musculus
• Alignment Length: 471
• Identity: 118/471 - (25%)
• Similarity: 191/471 - (40%)
• Gaps: 99/471 - (21%)

  Fly    83 RVIGMQKLWGTRIG----INRVWQGTAPRVLLFEPETVEPIL-----NSQKFVNKSHDYDYLHPW 138
            ||.|.:.:....:|    ::..|..:| |||| .|.||...:     |.:|..:|...::.|..:
Mouse    95 RVTGAENVRKILLGEHQLVSTEWPRSA-RVLL-GPNTVANSIGDIHRNKRKVFSKIFSHEALESY 157

  Fly   139 LGEGLLTSTD--RKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSEAFNLFPYVT 201
            |.:..|...|  |.|.|:             .:.|:|:.|... |..::||.|      |..:
Mouse   158 LPKIQLVIQDTLRAWSSQ-------------PEAINVYQEAQR-LTFRMAVRV------LLGF-- 200

  Fly   202 LCTLDIVCETAMGR--RIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQS 264
                 .:.|..:|.  .:|.|      :|:.|:.             |..|..||   .|:
Mouse   201 -----SIPEEDLGHLFEVYQQ------FVENVFS-------------LPVDLPFS---GYR---- 234

  Fly   265 YINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKE-GTVLS 328
                 .|.....|.::..|.||.::.......:..||            ||:||::||| |..::
Mouse   235 -----RGIQARQILQKGLEKAIREKLQCTQGKDYSDA------------LDILIESSKEHGKEMT 282

  Fly   329 NEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDS---IFGDDKETPATMK--N 388
            .:::::.....:|..:.||::|.:..:..|..||...|::.|||.:   :.|.......|::  .
Mouse   283 MQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAQGLLHGGGCPCEGTLRLDT 347

  Fly   389 LMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQF 453
            |..:|||:|.||:.:|||..|....|.|.:...:.|..:|.|...:......|....||.....|
Mouse   348 LSSLRYLDCVIKEVMRLFTPVSGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVF 412

  Fly   454 NPDNF---LPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRR-EDLT 514
            :||.|   ..|:..||  |.|:||..|.|.|:|:..|.|..|.:...:....:.|...|. ..:|
Mouse   413 DPDRFSQARSEDKDGR--FHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRIT 475

  Fly   515 LLGELILRPKDGLRVK 530
            |:.  :|.|.|||.||
Mouse   476 LVP--VLHPVDGLSVK 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	113/455 (25%)
Cyp26b1	NP_780684.1	CYP26B1	60..490	CDD:410730	118/471 (25%)