Protein Alignment Cyp4c3 and cyp-13A7

DIOPT Version :10

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_496114.1
• Gene: cyp-13A7 / 188362
• WormBaseID: WBGene00000372
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 141/585 - (24%)
• Similarity: 243/585 - (41%)
• Gaps: 128/585 - (21%)

  Fly    10 MAESILLSKVGQVISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEK-IPGPAAMPFLGNAIEM 73
            |:.|||::           |.:| :|.|..:|.:::       .:|.| :.||..:||||
 Worm     1 MSFSILIA-----------IAIF-VGIISYYLWIWS-------FWIRKGVKGPRGLPFLG----- 41

  Fly    74 NVDHDELFNRVIGMQKL--WGTRIG-INRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDY- 134
             |.|........|..|.  |..:.| :..:.:|....:::.:||.|..:     || |..|..|
 Worm    42 -VIHKFTNYENPGALKFSEWTKKYGPVYGITEGVEKTLVISDPEFVHEV-----FV-KQFDNFYG 99

  Fly   135 --LHPWLGE-------GLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKL-AVEV 189
              |....|:       .|:.:...:|...|.:.:|.|..|.|...:....|....|.|.| ....
 Worm   100 RKLTAIQGDPNKNKRVPLVAAQGHRWKRLRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKASA 164

  Fly   190 GSEAFNLFPYVTLCTLDIVCETAMGR-RIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDF-- 251
            ..:..::..|....|:||:.:.|||: :.....|...:.||.::..|     |.....:...|
 Worm   165 EGKTLDMLEYYQEFTMDIIGKMAMGQEKSLMFRNPMLDKVKTIFKEG-----RNNVFMISGIFPF 224

  Fly   252 -------IFSLTAEYKLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKK 309
                   ||:.....::.....:.|....|..:.:|:|:     |......:..|.
 Worm   225 VGIALRNIFAKFPSLQMATDIQSILEKALNKRLEQREAD-----EKAGIEPSGEPQ--------- 275

  Fly   310 RLAFLDLLIDASK-----EGTV---------------LSNEDIREEVDTFMFEGHDTTSAAISWT 354
              .|:||.:||..     ||..               |:.::|..::..|:..|:|||:.::|::
 Worm   276 --DFIDLFLDARSTVDFFEGEAEQDFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYS 338

  Fly   355 LFLLGCHPEYQERVVEELDSIFGDDKETP---ATMKNLMDMRYLECCIKDSLRLFPSVPMM-ARM 415
            .:||..|||.|:::.||:      |:|.|   .|...|..::||||.:|::|||:|...:: .|.
 Worm   339 SYLLATHPEIQKKLQEEV------DRECPDPEVTFDQLSKLKYLECVVKEALRLYPLASLVHNRK 397

  Fly   416 VGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFP------KPEQFNPDNFLPENCAGRHPF----A 470
            ..:..|:.|..:.|||...:.|::||.:|:|:.      |||::.         :|...|    .
 Worm   398 CLKTTNVLGMEIEAGTNINVDTWSLHHDPKVWGDDVNEFKPERWE---------SGDELFFAKGG 453

  Fly   471 YIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRRE-DLTLLGELILRPKDGLRVKITPR 534
            |:||..|||.|||.:.|::|.|.:::.:|:.|..|...... .|.|:|...:.|...| :|:..|
 Worm   454 YLPFGMGPRICIGMRLAMMEMKMLLTNILKNYTFETTPETVIPLKLVGTATIAPSSVL-LKLKSR 517

  Fly   535  534
             Worm   518  517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	117/489 (24%)
cyp-13A7	NP_496114.1	CYP3A-like	63..507	CDD:410678	115/485 (24%)