DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4c3 and cyp-31A5

DIOPT Version :9

Sequence 1:	NP_524598.1	Gene:	Cyp4c3 / 43663	FlyBaseID:	FBgn0015032	Length:	535	Species:	Drosophila melanogaster
Sequence 2:	NP_001343697.1	Gene:	cyp-31A5 / 13198891	WormBaseID:	WBGene00013381	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	297	Identity:	102/297 - (34%)
Similarity:	166/297 - (55%)	Gaps:	27/297 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VGQVISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNR 83
            :|.:|    |..:....:::.:|:..:.|..:::|::.:   |.:.|.:|:.:....|.:...|:
Worm     1 MGVII----PAVLLASATVIAWLIYKHLRMRQVLKHLNQ---PRSYPIVGHGLITKPDPEGFMNQ 58

  Fly    84 VIGMQKLW-GTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLLTST 147
            ||||..|: ..|:.:  :|.|..|.::|:..:.||||.:|.|.:||...|..|.||||..:|||.
Worm    59 VIGMGYLYPDPRMCL--LWIGPFPCLMLYSADLVEPIFSSTKHLNKGFAYVLLEPWLGISILTSQ 121

  Fly   148 DRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKL-AVEVGSEAFNLFPYVTLCTLDIVCET 211
            ..:|..:||:|||.||:.||.||:.:|||||.:|.:|| .:.|..|..::...:|||||||:|||
Worm   122 KEQWRPKRKLLTPTFHYDILKDFLPIFNEQSKILIQKLCCLGVADEEVDVLSVITLCTLDIICET 186

  Fly   212 AMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLHGFSNMV 276
            :||:.|.||....:|||.||:.|..::..|.....:.:.||::||.:.:.|:..::.||.|:..|
Worm   187 SMGKAIGAQLAENNEYVWAVHTINKLISKRTNNPLMWNSFIYNLTEDGRTHEKCLHILHDFTKKV 251

  Fly   277 IRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAF 313
            |.|||   ..||::             |...:.||||
Worm   252 IVERK---EALQDS-------------DYKMEGRLAF 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	96/257 (37%)
cyp-31A5	NP_001343697.1	p450	36..>261	CDD:325183	90/229 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	393	1.000	Inparanoid score	I1128
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		otm14469
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.870