Protein Alignment Cyp4c3 and Cyp4a14

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 533
• Identity: 169/533 - (31%)
• Similarity: 265/533 - (49%)
• Gaps: 72/533 - (13%)

  Fly    23 ISGYSPITVFLLGSILIFLVVYNK-----RRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFN 82
            |||:.. ..|||.   :|||::..     ||..|:|.::..|   .||
Mouse    15 ISGFFQ-WAFLLS---LFLVLFKAVQFYLRRQWLLKTLQHFP---CMP----------------- 55

  Fly    83 RVIGMQKLWGTRIGINR-----VW------------QGTAPRVLLFEPETVEPILNSQKFVNKSH 130
                ...|||..:....     :|            .|:..||||::|:.|:.:| .:.....|.
Mouse    56 ----SHWLWGHHLKDKELQQILIWVEKFPSACLQCLSGSNIRVLLYDPDYVKVVL-GRSDPKASG 115

  Fly   131 DYDYLHPWLGEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVGSE-AF 194
            .|.:..||:|.|||....:||...|::||||||:.||..::.:..:...::..|.....|.: ..
Mouse   116 IYQFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVNIMLDKWEKLDGQDHPL 180

  Fly   195 NLFPYVTLCTLDIVCETAMGRRIYAQSNSESE-YVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAE 258
            .:|..|:|.|||.|.:.|...:...|.:..|: |.|||..:.::...|....:.:.:.|::::::
Mouse   181 EIFHCVSLMTLDTVMKCAFSYQGSVQLDENSKLYTKAVEDLNNLTFFRLRNAFYKYNIIYNMSSD 245

  Fly   259 YKLHQSYINTLHGFSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKE 323
            .:|........|..::.||:.||::|...:|            .....||:.|.|||:|:.|..|
Mouse   246 GRLSHHACQIAHEHTDGVIKMRKSQLQNEEE------------LQKARKKRHLDFLDILLFARME 298

  Fly   324 G-TVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKETPATMK 387
            . ..||:||:|.|||||||||||||::.|||..:.|..|||:|:|..||:.||.||.  |..|..
Mouse   299 DRNSLSDEDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQQRCREEVQSILGDG--TSVTWD 361

  Fly   388 NLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNI-GGKIVPAGTQAIIMTYALHRNPRVFPKPE 451
            :|..|.|...|||::|||:|.|..::|.:...|.. .|:.:|.|..|.|..|.||.|||.:|.|:
Mouse   362 HLGQMPYTTMCIKEALRLYPPVISVSRELSSPVTFPDGRSIPKGITATISIYGLHHNPRFWPNPK 426

  Fly   452 QFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLL 516
            .|:|..|.|:  :..|..||:|||.|.|||||::||:.|.|..::..|.::::.....|..:. :
Mouse   427 VFDPSRFAPD--SSHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVP-I 488

  Fly   517 GELILRPKDGLRV 529
            ..|:|:.|:|:.:
Mouse   489 ARLVLKSKNGIHL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	156/492 (32%)
Cyp4a14	NP_031848.1	p450	52..501	CDD:278495	156/490 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844965
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650