Protein Alignment Cyp4c3 and Cyp3a13

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 544
• Identity: 141/544 - (25%)
• Similarity: 261/544 - (47%)
• Gaps: 79/544 - (14%)

  Fly    22 VISGYSPITVFLLGSILIFLVVYNKRRSRLVKYIEKIPGPAAMPFLGNAI-------EMNVDHDE 79
            :|..:|..|..||.:.|:.|.:|......:.|.: .||||..:||||..:       |.::...:
Mouse     3 LIPNFSMETWMLLATSLVLLYLYGTHSHGIFKKL-GIPGPKPLPFLGTILAYQKGFWECDIQCHK 66

  Fly    80 LFNRVIGMQKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQ---KFVNKSHDYDYLHP--WL 139
            .:.      |:||       ::.|..|.:.:.:|:.::.:|..:   .|.|:..    ..|  .|
Mouse    67 KYG------KMWG-------LYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRR----FGPVGIL 114

  Fly   140 GEGLLTSTDRKWHSRRKILTPAFHFKILDDFIDVFNEQSAVLARKLAVEVG-------SEAFNLF 197
            .:.:..|.:.:|...|.:|:|.|....|.:...:.|:.:.||.|.:...:|       .:.|..:
Mouse   115 KKAISISENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAY 179

  Fly   198 PYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDF---IFSLTAEY 259
                  ::|::..|:.|..|.:.:|.:..:|:.:            |..|:.|.   :|.....:
Mouse   180 ------SMDVITATSFGVNIDSLNNPQDPFVEKI------------KKLLKFDIFDPLFLSVTLF 226

  Fly   260 KLHQSYINTLHG--FSNMVIRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASK 322
            .......:.|:.  |...||......:..::||.....           :|:|:.||.|:|::..
Mouse   227 PFLTPVFDALNVSLFPRDVISFFTTSVERMKENRMKEK-----------EKQRVDFLQLMINSQN 280

  Fly   323 EGT-----VLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDSIFGDDKET 382
            ..|     .||:.:|..:...|:|.|::|||:|:|:.|:||..||:.|:::.:|:|:..  ..:.
Mouse   281 YKTKESHKALSDVEIVAQSVIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAAL--PNKA 343

  Fly   383 PATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVF 447
            |||...|:.|.||:..:.::|||:|....:.|:...||.|.|..:|.||..:|.|:|||::|:.:
Mouse   344 PATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYW 408

  Fly   448 PKPEQFNPDNFLPENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEAVDRRE- 511
            |:||:|.|:.|..:|....:|:.|:||.:|||||||.:||::..|..:..||:.:.::.....|
Mouse   409 PEPEEFRPERFSKKNQDSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEI 473

  Fly   512 DLTLLGELILRPKDGLRVKITPRD 535
            .|.|..:.:|:|::.|.:|:..||
Mouse   474 PLKLSKQGLLQPENPLLLKVVSRD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	128/501 (26%)
Cyp3a13	NP_031845.1	p450	39..491	CDD:365848	128/499 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810