Protein Alignment Cyp4c3 and Cyp26a1

DIOPT Version :9

• Sequence 1: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Alignment Length: 553
• Identity: 132/553 - (23%)
• Similarity: 220/553 - (39%)
• Gaps: 117/553 - (21%)

  Fly    27 SPITVFLLGSILIFLV---------VYNKRRSRLVKYIEKIPGPAAMPFLGNAIEMNVDH----- 77
            |.:..|:| .:|:||.         |.::.||..   :...||....||.|..::|.:..
Mouse     9 SALCTFVL-PLLLFLAALKLWDLYCVSSRDRSCA---LPLPPGTMGFPFFGETLQMVLQRRKFLQ 69

  Fly    78 -----------DELFN----RVIGMQKLWGTRIGINRVWQGTAPRVLLFEPETVEPILNSQKFVN 127
                       ..||.    ||:|..       .:.|:..|....|.:..|.:|..|
Mouse    70 MKRRKYGFIYKTHLFGRPTVRVMGAD-------NVRRILLGEHRLVSVHWPASVRTI-------- 119

  Fly   128 KSHDYDYLHPWLGEGLLTST-DRKWHSRRKILTPAFHFKILDDFIDVFNEQ-SAVLARKLAVEVG 190
                       ||.|.|::. |.....|:|::..||..:.|..::.|..|: |:.|.:.|:  .|
Mouse   120 -----------LGAGCLSNLHDSSHKQRKKVIMQAFSREALQCYVPVIAEEVSSCLEQWLS--CG 171

  Fly   191 SEAFNLFPYVTLCTLDIVCETAMGRRIYAQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSL 255
            .....::|.|......|.....:|.........|.|.        .:|::.:.    .:..:|||
Mouse   172 ERGLLVYPEVKRLMFRIAMRILLGCEPGPAGGGEDEQ--------QLVEAFEE----MTRNLFSL 224

  Fly   256 TAEYKLHQSYINTLHGFSNMV--IRERKAELAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLI 318
            ..:..           ||.:.  ::.|....|.::||.............|.|.|..   |.|||
Mouse   225 PIDVP-----------FSGLYRGVKARNLIHARIEENIRAKIRRLQATEPDGGCKDA---LQLLI 275

  Fly   319 DASKE-GTVLSNEDIREEVDTFMFEGHDTTSAAISWTLFLLGCHPEYQERVVEELDS---IFGDD 379
            :.|.| |..|..:.:::.....:|.||:||::|.:..:..||.:|...::|.||:.|   :...:
Mouse   276 EHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSN 340

  Fly   380 KETPATMKNLMDMRYLECCIKDSLRLFPSVPMMARMVGEDVNIGGKIVPAGTQAIIMTYALHRNP 444
            ::....|:.|..::|..|.||::|||.|.||...|:..:...:.|..:|.|...|......|...
Mouse   341 QDNKLDMETLEQLKYTGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVA 405

  Fly   445 RVFPKPEQFNPDNFL---PENCAGRHPFAYIPFSAGPRNCIGQKFAILEEKAVISTVLRKYKIEA 506
            .:|...|:||||.|:   ||: |.|  |::|||..|.|:|:|::||        ..:|:.:.:|
Mouse   406 DIFTNKEEFNPDRFIVPHPED-ASR--FSFIPFGGGLRSCVGKEFA--------KILLKIFTVE- 458

  Fly   507 VDRREDLTLL-GELILR------PKDGLRVKIT 532
            :.|..|..|| |...::      |.|.|..:.|
Mouse   459 LARHCDWQLLNGPPTMKTSPTVYPVDNLPARFT 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4c3	NP_524598.1	p450	59..531	CDD:278495	122/509 (24%)
Cyp26a1	NP_031837.2	p450	43..491	CDD:299894	122/513 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910